AP-18__TRPA1 blocker GS-9973
Product Name
AP-18
Description
TRPA1 blocker
Purity
>98%
CAS No.
55224-94-7
Molecular Formula
C11H12ClNO
Molecular Weight
209.67
Storage Temperature
-20ºC
Shipping Temperature
Shipped Ambient
Product Type
Inhibitor
Solubility
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Source
Synthetic
Appearance
White Solid
SMILES
C/C(=CC1=CC=C(C=C1)Cl)/C(=N/O)/C
InChI
InChI=1S/C11H12ClNO/c1-8(9(2)13-14)7-10-3-5-11(12)6-4-10/h3-7,14H,1-2H3/b8-7-,13-9+
InChIKey
MHTJEUOFLVQMCL-XTYDYKDCSA-N
Safety Phrases
Classification: Caution: Substance not yet fully tested.
Safety Phrases:
S22 – Do not breathe dust
S24/25 – Avoid contact with skin and eyes
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
Hazard Phrases: H302
Cite This Product
AP-18 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-310)
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/19114658
Alternative Names
(2E,3E)-4-(4-Chlorophenyl)-N-hydroxy-3-methyl-3-buten-2-imine
Research Areas
Ion Channels, Neuroscience, Transient Receptor Potential Channels
PubChem ID
16725814
Scientific Background
AP-18 is a reversible TRPA1 channel blocker. They exhibit fibroblast-like morphology, slow growth and contact inhibition (1).
References
1. Doi H., et al. (2005) Tohoku J Exp Med. 207(3): 209-216.
TRPA1 blocker
Safety Phrases:
S22 – Do not breathe dust
S24/25 – Avoid contact with skin and eyes
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
Hazard Phrases: H302