AS 041164__PI 3-Kgamma kinase inhibitor XMU-MP-1
Product Name
AS 041164
Description
PI 3-Kgamma kinase inhibitor
Purity
>98% (TLC)
CAS No.
6318-41-8
Molecular Formula
C11H7NO4S
Molecular Weight
249.2
Storage Temperature
-20ºC
Shipping Temperature
Shipped Ambient
Product Type
Inhibitor
Solubility
Soluble in DMSO (25 mg/ml). For in vivo administration this compound was suspended in 0.5% carboxymethylcellulose/0.25% Tween 20 as a vehicle
Source
Synthetic
Appearance
Yellow solid
SMILES
C2=C(C=C1/C(NC(S1)=O)=O)C=CC3=C2OCO3
InChI
InChI=1S/C11H7NO4S/c13-10-9(17-11(14)12-10)4-6-1-2-7-8(3-6)16-5-15-7/h1-4H,5H2,(H,12,13,14)
InChIKey
SDGWAUUPHUBJNQ-UHFFFAOYSA-N
Safety Phrases
Classification:
Not a hazardous substance or mixture.
Safety Phrases:
S22 – Do not breathe dust.
S24/25 – Avoid contact with skin and eyes.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.
Cite This Product
AS 041164 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-433)
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/19114889
Alternative Names
NSC31098, 5-Benzo[1,3]dioxol-5-ylmethylene-thiazolidine-2,4-dione
Research Areas
Cancer, Apoptosis, Cancer Growth Inhibitors, Cell Signaling, Tyrosine Kinase Inhibitors
PubChem ID
233033
Scientific Background
AS 041164 is a selective PI 3-Kγ isoform inhibitor. It also blocks neutrophil migration.
References
1. Ferrandi C., et al. (2007) J. Pharmacol. Exp.Ther. 322(3): 923–930.
PI 3-Kgamma kinase inhibitor
Not a hazardous substance or mixture.
Safety Phrases:
S22 – Do not breathe dust.
S24/25 – Avoid contact with skin and eyes.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.