Ambroxol HCl

Ambroxol HCl__Free radical scavenger Palovarotene

Product Name Ambroxol HCl
Description

Free radical scavenger

Purity >98%
CAS No. 23828-92-4
Molecular Formula C13H18Br2N2O•HCl
Molecular Weight 414.57
Storage Temperature -20ºC
Shipping Temperature Shipped Ambient
Product Type Antioxidant
Solubility Soluble to 50 mM in DMSO
Source Synthetic
Appearance White Solid
SMILES C1CC(CCC1NCC2=C(C(=CC(=C2)Br)Br)N)O
InChI InChI=1S/C13H18Br2N2O/c14-9-5-8(13(16)12(15)6-9)7-17-10-1-3-11(18)4-2-10/h5-6,10-11,17-18H,1-4,7,16H2
InChIKey JBDGDEWWOUBZPM-UHFFFAOYSA-N
Safety Phrases Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin.
Safety Phrases:
S22 – Do not breathe dust
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
S45- In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible)
Hazard Phrases:
H302
Cite This Product Ambroxol HCl (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-153)

References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/1911391

Alternative Names 4-[(2-Amino-3,5-dibromobenzyl)amino]cyclohexanol
Research Areas Cancer, Oxidative Stress
PubChem ID 2132
Scientific Background Ambroxol is a very potent inhibitor of the neuronal sodium channels (1). It is also a mucolytic agent with antioxidant, anti-viral and anti-inflammatory properties, and has been used effectively with respiratory diseases, and as throat logenzes (2).
References 1. Weiser T. (2006) Neurosci Lett. 395: 179-184.
2. Sanderson R.J., et al. (1976) Respir Phys. 27: 379-392.