BML-210__HDAC inhibitor PF-04691502
Product Name
BML-210
Description
HDAC inhibitor
Purity
>98% (TLC); NMR (Conforms)
CAS No.
537034-17-6
Molecular Formula
C20H25N3O2
Molecular Weight
339.4
Storage Temperature
-20ºC
Shipping Temperature
Shipped Ambient
Product Type
Inhibitor
Solubility
Soluble in 25 mg/ml DMSO or 10 mg/ml Ethanol
Source
Synthetic
Appearance
Tan Solid
SMILES
C1=CC=C(C=C1)NC(=O)CCCCCCC(=O)NC2=CC=CC=C2N
InChI
InChI=1S/C20H25N3O2/c21-17-12-8-9-13-18(17)23-20(25)15-7-2-1-6-14-19(24)22-16-10-4-3-5-11-16/h3-5,8-13H,1-2,6-7,14-15,21H2,(H,22,24)(H,23,25)
InChIKey
RFLHBLWLFUFFDZ-UHFFFAOYSA-N
Safety Phrases
Classification: Caution- Substance not yet fully tested.
Safety Phrases:
S22 – Do not breathe dust
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
S24/25- Avoid contact with skin and eyes
Hazard Statements:
H413 – May cause long lasting harmful effects to aquatic life.
Cite This Product
Bml-210 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-348)
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/19116637
Alternative Names
N1-(2-aminophenyl)-N8-phenyloctanediamide
Research Areas
Cancer, Cell Signaling, Epigenetics
PubChem ID
9543540
Scientific Background
A novel non-hydroxamic acid HDAC inhibitor. IC50=5-10 µM (HeLa nuclear extract). Induces growth inhibition, proapoptotic and differentiation effects on human leukemia cell lines.
References
1. Savickiene J., et al. (2006) Eur. J. Pharmacol. 549: 9.
2. Herman D., et al. (2006) Nature Chem. Biol. 10: 551.
HDAC inhibitor
Safety Phrases:
S22 – Do not breathe dust
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
S24/25- Avoid contact with skin and eyes
Hazard Statements:
H413 – May cause long lasting harmful effects to aquatic life.
2. Herman D., et al. (2006) Nature Chem. Biol. 10: 551.