BML 259__CDK5, p25 kinase inhibitor PF-04447943
Product Name
BML 259
Description
CDK5, p25 kinase inhibitor
Purity
>98% (TLC)
CAS No.
267654-00-2
Molecular Formula
C14H16N2OS
Molecular Weight
260.4
Storage Temperature
-20ºC
Shipping Temperature
Shipped Ambient
Product Type
Inhibitor
Solubility
Soluble in DMSO (30 mg/ml), dimethyl formamide (30 mg/ml) or 100% ethanol (0.25 mg/ml)
Source
Synthetic
Appearance
White solid
SMILES
CC(C)C1=CN=C(S1)NC(=O)CC2=CC=CC=C2
InChI
InChI=1S/C14H16N2OS/c1-10(2)12-9-15-14(18-12)16-13(17)8-11-6-4-3-5-7-11/h3-7,9-10H,8H2,1-2H3,(H,15,16,17)
InChIKey
IGRZXNLKVUEFDM-UHFFFAOYSA-N
Safety Phrases
Classification:
Not a hazardous substance or mixture.
Safety Phrases:
S22 – Do not breathe dust.
S24/25 – Avoid contact with skin and eyes.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.
Cite This Product
Bml 259 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-435)
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/1911659
Alternative Names
N-(5-Isopropylthiazol-2-yl)phenylacetamide
Research Areas
Cancer, Apoptosis, Cancer Growth Inhibitors, Cell Signaling, Tyrosine Kinase Inhibitors
PubChem ID
16760027
Scientific Background
Bml 259 is a potent inhibitor of Cdk5/p25. It also inhibits Cdk2/cyclin E.
References
1. Kaźmierczak A., Czapski G.A., Adamczyk A., Gajkowska B., & Strosznajder J.B. (2011) Neurochem. Int. 58(2): 206–214.
CDK5, p25 kinase inhibitor
Not a hazardous substance or mixture.
Safety Phrases:
S22 – Do not breathe dust.
S24/25 – Avoid contact with skin and eyes.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.