BRD 7389__p90 RSK kinase inhibitor Exendin-4
Product Name
BRD 7389
Description
p90 RSK kinase inhibitor
Purity
>98% (HPLC)
CAS No.
376382-11-5
Molecular Formula
C24H18N2O2
Molecular Weight
366.4
Storage Temperature
-20ºC
Shipping Temperature
Shipped Ambient
Product Type
Inhibitor
Solubility
Soluble to 100 mM in DMSO
Source
Synthetic
Appearance
Orange powder
SMILES
C1=CC=C(C=C1)CCNC2=C3C4=CC=CC=C4C(=O)C5=C3C(=CC=C5)NC2=O
InChI
InChI=1S/C24H18N2O2/c27-23-17-10-5-4-9-16(17)21-20-18(23)11-6-12-19(20)26-24(28)22(21)25-14-13-15-7-2-1-3-8-15/h1-12,20,25H,13-14H2
InChIKey
QVEVXIXBUORVGE-UHFFFAOYSA-N
Safety Phrases
Classification:
Not a hazardous substance or mixture.
Safety Phrases:
S22 – Do not breathe dust.
S24/25 – Avoid contact with skin and eyes.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.
Cite This Product
BRD 7389 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-497)
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/19116683
Alternative Names
BRD7389, BRD-7389, 1-(2-Phenylethyl)amino-3H-naphtho1,2,3-dequinoline-2,7-dione, 1-Phenethylamino-3H-naphtho1,2,3-dequinoline-2,7-dione
Research Areas
Cancer, Apoptosis, Cancer Growth Inhibitors, Cell Signaling, Tyrosine Kinase Inhibitors
PubChem ID
24870634
Scientific Background
BRD 7389 is a p90 ribosomal S6 kinase (RSK) inhibitor. Specifically, BRD7398 inhibits RSK1, RSK2 and RSK3. This compound has been seen to unregulate insulin expression in terminally differentiated pancreatic &alpha-cells.
References
1. Fomina-Yadlin D., et al. (2010) Pro. Nat. Acad.Sci. USA. 107(34): 15099–15104.
p90 RSK kinase inhibitor
Not a hazardous substance or mixture.
Safety Phrases:
S22 – Do not breathe dust.
S24/25 – Avoid contact with skin and eyes.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.