Bexarotene__Retinoid RXR agonist INCB3344
Product Name
Bexarotene
Description
Retinoid RXR agonist
Purity
>98% (TLC); NMR (Conforms)
CAS No.
153559-49-0
Molecular Formula
C24H28O2
Molecular Weight
348.5
Storage Temperature
-20ºC
Shipping Temperature
Shipped Ambient
Product Type
Agonist
Solubility
Soluble in DMSO (60 mg/ml) or ethanol (warm, 10 mg/ml)
Source
Synthetic
Appearance
White powder
SMILES
Cc1cc2c(cc1C(=C)c3ccc(cc3)C(=O)O)C(CCC2(C)C)(C)C
InChI
InChI=1S/C24H28O2/c1-15-13-20-21(24(5,6)12-11-23(20,3)4)14-19(15)16(2)17-7-9-18(10-8-17)22(25)26/h7-10,13-14H,2,11-12H2,1,3-6H3,(H,25,26)
InChIKey
NAVMQTYZDKMPEU-UHFFFAOYSA-N
Safety Phrases
Classification:
Not a hazardous substance or mixture.
Safety Phrases:
S22 – Do not breathe dust.
S24/25 – Avoid contact with skin and eyes.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.
Cite This Product
Bexarotene (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-535)
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/19116375
Alternative Names
SR 11247, Targretin, 4-1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenylbenzoic acid
Research Areas
Cancer, Cancer Growth Inhibitors, Cell Signaling, Epigenetics and Nuclear Signalling, Neurodegeneration, Neuroscience, Nuclear Signaling Pathways
PubChem ID
82146
Scientific Background
Bexarotene is a potent RXR agonist. It is able to permeate the blood-brain barrier. Bexarotene inhibits neurodegeneration and has anti-tumor properties.
Retinoid RXR agonist
Not a hazardous substance or mixture.
Safety Phrases:
S22 – Do not breathe dust.
S24/25 – Avoid contact with skin and eyes.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.