BzATP__Prototypic P2X7 receptor agonist NVP-BGJ398
Product Name
BzATP
Description
Prototypic P2X7 receptor agonist
Purity
97.7%
CAS No.
112898-15-4
Molecular Formula
C24H24N5O15P3•C18H45N3
Molecular Weight
1018.97
Storage Temperature
-20ºC
Shipping Temperature
Shipped Ambient
Product Type
Agonist
Solubility
Soluble in water.
Source
Synthetic
Appearance
Off white solid
SMILES
email protected3(OC@@H(C@@H(OC(=O)C1=CC=C(C=C1)C(=O)C2=CC=CC=C2)email protected3O)COP(OP(OP(=O)(O)O)(=O)O)(=O)O)N4C5=C(N=C4)C(=NC=N5)N
InChI
InChI=1S/C24H24N5O15P3.C6H15N/c25-21-17-22(27-11-26-21)29(12-28-17)23-19(31)20(16(41-23)10-40-46(36,37)44-47(38,39)43-45(33,34)35)42-24(32)15-8-6-14(7-9-15)18(30)13-4-2-1-3-5-13;1-4-7(5-2)6-3/h1-9,11
InChIKey
HVOVBTNCGADRTH-WBLDMZOZSA-N
Safety Phrases
Classification: Not WHMIS controlled.
Safety Phrases:
S22 – Do not breathe dust.
S24/25 – Avoid contact with skin and eyes.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.
Cite This Product
BzATP (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-420)
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/19116923
Alternative Names
2'(3')-O-(4-Benzoylbenzoyl)adenosine-5'-triphosphate tri(triethylammonium) salt
Research Areas
Ion Channels, Neuroscience
PubChem ID
71308559
Scientific Background
BzATP triethylammonium salt is a prototypic P2X7 receptor agonist that exhibits 5 – 10 fold greater potency than ATP. This small molecule also exhibits partial agonist activity at P2X1 and P2Y1 receptors. Lastly, it can be used as a photoaffinity label for ATPase.
References
1. Young M., Pelegrin P., & Surprenant A. (2007) Mol Pharmacol. 92-100.
Prototypic P2X7 receptor agonist
Safety Phrases:
S22 – Do not breathe dust.
S24/25 – Avoid contact with skin and eyes.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.