C8 Ceramide__Protein kinase activator LDE225 (Diphosphate)
Product Name
C8 Ceramide
Description
Protein kinase activator
Purity
>98% (TLC)
CAS No.
74713-59-0
Molecular Formula
C26H51NO3
Molecular Weight
425.7
Storage Temperature
-20ºC
Shipping Temperature
Shipped Ambient
Product Type
Activator
Solubility
Soluble in DMSO (25 mg/ml) or 100% ethanol (25 mg/ml)
Source
Synthetic
Appearance
White waxy solid
SMILES
CCCCCCCCCCCCC/C=C/email protected(email protected(CO)NC(=O)CCCCCCC)O
InChI
InChI=1S/C26H51NO3/c1-3-5-7-9-10-11-12-13-14-15-16-18-19-21-25(29)24(23-28)27-26(30)22-20-17-8-6-4-2/h19,21,24-25,28-29H,3-18,20,22-23H2,1-2H3,(H,27,30)/b21-19+/t24-,25+/m0/s1
InChIKey
APDLCSPGWPLYEQ-WRBRXSDHSA-N
Safety Phrases
Classification:
Not a hazardous substance or mixture.
Safety Phrases:
S22 – Do not breathe dust.
S24/25 – Avoid contact with skin and eyes.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.
Cite This Product
C8 Ceramide (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-499)
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/19117330
Alternative Names
C8-Ceramide
Research Areas
Cell Signaling
PubChem ID
5702614
Scientific Background
C8 Ceramide is a biologically active ceramide analog. It is a protein kinase activator. It has also been shown to induce phosphorylation of EGF, as well as, apoptosis in vitro.
References
1. Józefowski S., et al. (2010) J. Immun. (Baltimore, Md.: 1950). 185(11): 6960–6973.
2. Gusain A., et al. (2012) Mol.Neurobio. 45(3): 455–464.
Protein kinase activator
Not a hazardous substance or mixture.
Safety Phrases:
S22 – Do not breathe dust.
S24/25 – Avoid contact with skin and eyes.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.
2. Gusain A., et al. (2012) Mol.Neurobio. 45(3): 455–464.