Clozapine__Dopamine receptor antagonist Empagliflozin
Product Name
Clozapine
Description
Dopamine receptor antagonist
Purity
>98% (TLC); NMR (Conforms)
CAS No.
5786-21-0
Molecular Formula
C18H19ClN4
Molecular Weight
326.8
Storage Temperature
-20ºC
Shipping Temperature
Shipped Ambient
Product Type
Antagonist
Solubility
Soluble in DMSO (30 mg/ml)
Source
Synthetic
Appearance
Yellow powder
SMILES
CN1CCN(CC1)C2=C3C=CC=CC3=Nc4ccc(Cl)cc4N2
InChI
1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3
InChIKey
ZUXABONWMNSFBN-UHFFFAOYSA-N
Safety Phrases
Classification:
D1B Toxic Material Causing Immediate and Serious Toxic Effects – Toxic by ingestion
D2A Very Toxic Material Causing Other Toxic Effects – Teratogen
D2B Toxic Material Causing Other Toxic Effects – Carcinogen, Moderate eye irritant, Mutagen
Hazard statement(s):
H301 Toxic if swallowed.
H341 Suspected of causing genetic defects.
H351 Suspected of causing cancer.
H361 Suspected of damaging fertility or the unborn child.
Precautionary statement(s):
P281 Use personal protective equipment as required.
P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/ physician.
Cite This Product
Clozapine (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-541-250MG)
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/19119094
Alternative Names
3-chloro-6-(4-methylpiperazin-1-yl)-5H-benzoc1,5benzodiazepine, 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzob,e1,4-diazepine, Clozapine, Leponex, Clozapin, CLOZARIL, Fazaclo
Research Areas
Neuroscience, Neurotransmitter Receptors
PubChem ID
2818
Scientific Background
Clozapine is a atypical antipsychotic. It binds several types of receptors in the brain, and acts as a serotonin antagonist. Predicted to act through 5-HT 2A/2C and dopamine receptor blockade.
Dopamine receptor antagonist
D1B Toxic Material Causing Immediate and Serious Toxic Effects – Toxic by ingestion
D2A Very Toxic Material Causing Other Toxic Effects – Teratogen
D2B Toxic Material Causing Other Toxic Effects – Carcinogen, Moderate eye irritant, Mutagen
Hazard statement(s):
H301 Toxic if swallowed.
H341 Suspected of causing genetic defects.
H351 Suspected of causing cancer.
H361 Suspected of damaging fertility or the unborn child.
Precautionary statement(s):
P281 Use personal protective equipment as required.
P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/ physician.