D-AP5.Na__NMDA receptor antagonist OTS-964
Product Name
D-AP5.Na
Description
NMDA receptor antagonist
Purity
>99.5
CAS No.
14375-45-2
Molecular Formula
C5H12NO5P.Na
Molecular Weight
219.11
Storage Temperature
-20ºC
Shipping Temperature
Shipped Ambient
Product Type
Antagonist
Solubility
Soluble in 1 M NH4OH (50 mg/ml); water (9 mg/ml).
Source
Synthetic
Appearance
White solid
SMILES
C@@H(NH3+)(CCCP(O-)(O-)=O)C(O-)=O
Safety Phrases
Classification: Not WHMIS controlled.
Safety Phrases:
S22 – Do not breathe dust.
S24/25 – Avoid contact with skin and eyes.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.
Cite This Product
D-AP5.Na (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-412)
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/19120130
Alternative Names
D-amino-5-phosphonopentaoic acid sodium salt
Research Areas
Glutamate Receptors, Ion Channels, Neuroscience, Neurotransmitter Receptors, NMDA Receptors
Scientific Background
DAP5 is used widely as a potent and selective NMDA receptor antagonist. It represents the active enantiomer form of AP5 (2-amino-5-phosphonopentanoic acid).
References
1. Davies J., & Watkins J. (1982) Brain Res. 378-86.
2. Schulte M., Roon R., Chalmers D., Sunter D., & Koerner J. (1994) Brain Res. 203-7.
NMDA receptor antagonist
Safety Phrases:
S22 – Do not breathe dust.
S24/25 – Avoid contact with skin and eyes.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.
2. Schulte M., Roon R., Chalmers D., Sunter D., & Koerner J. (1994) Brain Res. 203-7.