D-LAP5.Na

D-LAP5.Na__NMDA receptor antagonist Romidepsin

Product Name D-LAP5.Na
Description

NMDA receptor antagonist

Purity >99.0
CAS No. 1303993-72-7
Molecular Formula C5H12NO5P•Na
Molecular Weight 219.11
Storage Temperature -20ºC
Shipping Temperature Shipped Ambient
Product Type Antagonist
Solubility Soluble to 100 mM in water
Source Synthetic
Appearance White solid
SMILES C(P(O)(O)=O)CCC(C(O)=O)N
Safety Phrases Classification: Not WHMIS controlled.
Safety Phrases:
S22 – Do not breathe dust.
S24/25 – Avoid contact with skin and eyes.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.
Cite This Product D-LAP5.Na (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-414)

References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/19120261

Alternative Names DL-amino-5-phosphonopentaoic acid sodium salt
Research Areas Glutamate Receptors, Ion Channels, Neuroscience, Neurotransmitter Receptors, NMDA Receptors
Scientific Background DLAP5 is a racemic mixture. It is used widely as a potent and selective NMDA receptor antagonist. It represents the active enantiomer form of AP5 (2-amino-5-phosphonopentanoic acid).
References 1. Davies J., & Watkins J. (1982) Brain Res. 378-86.
2. Schulte M., Roon R., Chalmers D., Sunter D., & Koerner J. (1994) Brain Res. 203-7.