Deprenyl__Apoptosis Inhibitor ICG-001
Product Name
Deprenyl
Description
Apoptosis Inhibitor
Purity
>99%
CAS No.
14611-52-0
Molecular Formula
C13H17N·HCl
Molecular Weight
223.74
Storage Temperature
-20ºC
Shipping Temperature
Shipped Ambient
Product Type
Inhibitor
Solubility
Soluble to 100 mM in water, and to 100 mM in ethanol
Source
Synthetic
Appearance
White Solid
SMILES
Cemail protected(CC1=CC=CC=C1)N(C)CC#C
InChI
InChI=1S/C13H17N.ClH/c1-4-10-14(3)12(2)11-13-8-6-5-7-9-13;/h1,5-9,12H,10-11H2,2-3H3;1H/t12-;/m1./s1
InChIKey
IYETZZCWLLUHIJ-UTONKHPSSA-N
Safety Phrases
Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin.
Safety Phrases:
S22 – Do not breathe dust
S24/25 – Avoid contact with skin and eyes
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
Risk Phrases:
R62- Possible risk of impaired fertility
Cite This Product
Deprenyl (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-209)
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/19120324
Alternative Names
N-Methyl-N-(2R)-1-phenyl-2-propanyl-2-propyn-1-amine, Selegiline
Research Areas
Cancer, Apoptosis
PubChem ID
26757
Scientific Background
Deprenyl or Selegiline is a drug used for the treatment of early stage Parkinson’s (1), depression and senile dementia (2). It is a selective irreversable inhibitor of monoamine oxidase B (MAO-b).
References
1. Lachenmayer L., and Laux G. (2004) Curr Med Chem. 11(15): 2033-2043.
2. FDA US Food and Drug Administration. Press Announcements Feb 28, 2006. www.fda.gov/newsevents/newsroom/pressannouncements/2006/ucm108607.htm
Apoptosis Inhibitor
Safety Phrases:
S22 – Do not breathe dust
S24/25 – Avoid contact with skin and eyes
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
Risk Phrases:
R62- Possible risk of impaired fertility
2. FDA US Food and Drug Administration. Press Announcements Feb 28, 2006. www.fda.gov/newsevents/newsroom/pressannouncements/2006/ucm108607.htm