Edaravone__Free radical scavenger MK-5172
Product Name
Edaravone
Description
Free radical scavenger
Purity
>98%
CAS No.
89-25-8
Molecular Formula
C10H10N2O
Molecular Weight
174.2
Storage Temperature
-20ºC
Shipping Temperature
Shipped Ambient
Product Type
Antioxidant
Solubility
Soluble to 100 mM in DMSO
Source
Synthetic
Appearance
Light Yellow Solid
SMILES
CC1=NN(C(=O)C1)C2=CC=CC=C2
InChI
InChI=1S/C10H10N2O/c1-8-7-10(13)12(11-8)9-5-3-2-4-6-9/h2-6H,7H2,1H3
InChIKey
QELUYTUMUWHWMC-UHFFFAOYSA-N
Safety Phrases
Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin.
Safety Phrases:
S22 – Do not breathe dust
S24/25 – Avoid contact with skin and eyes
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
Risk Phrases:
R20/21/22 – Harmful by inhalation, in contact with skin and if swallowed
R62 – Possible risk of impaired fertility
R68 – Possible risk of irreversible effects
Hazard Phrases:
H302-H315-H319-H335
Precautionary Phrases: P261-P305 + P351 + P338
Cite This Product
Edaravone (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-152)
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/19122446
Alternative Names
5-Methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, MCI-186
Research Areas
Cancer, Oxidative Stress
PubChem ID
4021
Scientific Background
A radical scavenger and antioxidant which is able to protect against the effects of ischemia by inhibiting the lipoxygenase system. Protects against MPTP-induced neurotoxicity.
References
1. Kawai G., et al. (1997) J Pharmacol Exp Ther. 281(2): 921-927.
2. Yuki S., and Koqure K. (1997) Mol Chem Neuropathol. 32(1-3): 123-128.
Free radical scavenger
Safety Phrases:
S22 – Do not breathe dust
S24/25 – Avoid contact with skin and eyes
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
Risk Phrases:
R20/21/22 – Harmful by inhalation, in contact with skin and if swallowed
R62 – Possible risk of impaired fertility
R68 – Possible risk of irreversible effects
Hazard Phrases:
H302-H315-H319-H335
Precautionary Phrases: P261-P305 + P351 + P338
2. Yuki S., and Koqure K. (1997) Mol Chem Neuropathol. 32(1-3): 123-128.