FCCP__MPTP inhibitor GANT 61
Product Name
FCCP
Description
MPTP inhibitor
Purity
>98%
CAS No.
370-86-5
Molecular Formula
C10H5F3N4O
Molecular Weight
254.17
Storage Temperature
-20ºC
Shipping Temperature
Shipped Ambient
Product Type
Inducer
Solubility
Soluble to 100 mM in DMSO
Source
Synthetic
Appearance
Yellow solid
SMILES
C1=CC(=CC=C1NN=C(C#N)C#N)OC(F)(F)F
InChI
InChI=1S/C2H6FP/c3-1-2-4/h1-2,4H2
InChIKey
GYQDBNYYNSTQTM-UHFFFAOYSA-N
Safety Phrases
Classification: Toxic. May be harmful or fatal if inhaled, swallowed or absorbed through skin.
Safety Phrases:
S22 – Do not breathe dust
S24/25 – Avoid contact with skin and eyes
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
Risk Phrases:
R23/24/25- Toxic by inhalation, in contact with skin, and if swallowed
Hazard Phrases:
H301-H317-H319-H413
Precautionary Phrases:
P280-P301 + P310-P305 + P351 + P338
Cite This Product
FCCP (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-222)
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/19124024
Alternative Names
{4-(Trifluoromethoxy)phenylhydrazono}malononitrile
Research Areas
Cancer, Apoptosis
PubChem ID
3330
Scientific Background
FCCP is a tool for inhibiting mitochondrial oxidative phosphorylation (1, 2).
References
1. Collins T.J., et al. (2000) Biochem J. 347: 593.
2. Keij J.F., et al. (2000) Cytometry 39: 203.
MPTP inhibitor
Safety Phrases:
S22 – Do not breathe dust
S24/25 – Avoid contact with skin and eyes
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
Risk Phrases:
R23/24/25- Toxic by inhalation, in contact with skin, and if swallowed
Hazard Phrases:
H301-H317-H319-H413
Precautionary Phrases:
P280-P301 + P310-P305 + P351 + P338
2. Keij J.F., et al. (2000) Cytometry 39: 203.