Flupirtine maleate

Flupirtine maleate__Kv7 channel activator Verubecestat

Product Name	Flupirtine maleate
Description	Kv7 channel activator
Purity	>98% (HPLC)
CAS No.	75507-68-5
Molecular Formula	C15H17FN4O2•C4H4O4
Molecular Weight	420.4

Storage Temperature	-20ºC
Shipping Temperature	Shipped Ambient
Product Type	Activator
Solubility	Soluble in DMSO (100 mM) and ethanol (10 mM)
Source	Synthetic
Appearance	White solid
SMILES	CCOC(=O)NC1=C(N=C(C=C1)NCC2=CC=C(C=C2)F)N.C(=CC(=O)O)C(=O)O
InChI	InChI=1S/C15H17FN4O2.C4H4O4/c1-2-22-15(21)19-12-7-8-13(20-14(12)17)18-9-10-3-5-11(16)6-4-10;5-3(6)1-2-4(7)8/h3-8H,2,9H2,1H3,(H,19,21)(H3,17,18,20);1-2H,(H,5,6)(H,7,8)/b;2-1-
InChIKey	DPYIXBFZUMCMJM-BTJKTKAUSA-N
Safety Phrases	Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 – Do not breathe dust S24/25 – Avoid contact with skin and eyes S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
Cite This Product	Flupirtine maleate (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-376)

References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/19124645

Alternative Names	N-2-Amino-6-4-fluorophenyl)methy-lamino-3-pyridinylcarbamic acid ethyl ester maleate
Research Areas	Ion Channels, Neuroscience, Potassium Channels, Voltage-Gated Potassium Channels
PubChem ID	6435335
Scientific Background	Flupirtine maleate is a triaminopyridine derivative salt. It has non-opioid analgesic, neuroprotection, antiapoptic and muscle relaxation properties. Oral Flupirtine provides the same analgesic pain relief administered to individuals without the side effects of non-steroidal anti-inflammatory drugs (1-2).
References	1. Naser SM., Sarkar N., Biswas A., Kamal F., Prakash R., Rahaman QM., Das AK. (2012) J Indian med Assoc. 110(3): 158-60. 2. Harish S., Bhuvana K., Bengalorkar G. and Kumar TN. (2012) J Anaethesiol Clin Pharmacol. 28(2): 172-177.