Idebenone

Idebenone__Quinone antioxidant BLZ946

Product Name Idebenone
Description

Quinone antioxidant

Purity >98% (TLC and HPLC); NMR (Conforms)
CAS No. 58186-27-9
Molecular Formula C19H30O5
Molecular Weight 338.44
Storage Temperature -20ºC
Shipping Temperature Shipped Ambient
Product Type Antioxidant
Solubility Soluble to 100 mM in DMSO, 100 mM in ethanol
Source Synthetic
Appearance Orange Solid
SMILES CC1=C(C(=O)C(=C(C1=O)OC)OC)CCCCCCCCCCO
InChI InChI=1S/C19H30O5/c1-14-15(12-10-8-6-4-5-7-9-11-13-20)17(22)19(24-3)18(23-2)16(14)21/h20H,4-13H2,1-3H3
InChIKey JGPMMRGNQUBGND-UHFFFAOYSA-N
Safety Phrases Classification: Caution: Substance not yet fully tested.
Safety Phrases:
S22 – Do not breathe dust
S24/25 – Avoid contact with skin and eyes
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
Cite This Product Idebenone (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-150)

References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/19132784

Alternative Names 2-(10-Hydroxydecyl)-5,6-dimethoxy-3-methyl-1,4-benzoquinone
Research Areas Cancer, Oxidative Stress
PubChem ID 3686
Scientific Background Idebenone has been tested for numerous pharmaceutical indications including Alzheimer’s (1), Friedreich’s ataxia (2), and Duchenne muscular dystrophy. It also has similar antioxidant properties to CoQ10, and has therefore been used in anti-aging applications as well (3).
References 1. Gutzmann H., Kuhl K.P., Hadler D and Rapp M.A. (2002) Pharmacopsychiatry. 35(1): 12-18.
2. Di Prospero N.A., Baker A., Jeffries N, Fischbeck K.H. (2007) Lancet Neuro. 6(10): 878-886.
3. McDaniel D., Neudecker B., Dinardo J, Lewis J., Maibach H. (2005) Cosmet Dermatol. 4(3): 167-173.