Idebenone__Quinone antioxidant BLZ946
Product Name
Idebenone
Description
Quinone antioxidant
Purity
>98% (TLC and HPLC); NMR (Conforms)
CAS No.
58186-27-9
Molecular Formula
C19H30O5
Molecular Weight
338.44
Storage Temperature
-20ºC
Shipping Temperature
Shipped Ambient
Product Type
Antioxidant
Solubility
Soluble to 100 mM in DMSO, 100 mM in ethanol
Source
Synthetic
Appearance
Orange Solid
SMILES
CC1=C(C(=O)C(=C(C1=O)OC)OC)CCCCCCCCCCO
InChI
InChI=1S/C19H30O5/c1-14-15(12-10-8-6-4-5-7-9-11-13-20)17(22)19(24-3)18(23-2)16(14)21/h20H,4-13H2,1-3H3
InChIKey
JGPMMRGNQUBGND-UHFFFAOYSA-N
Safety Phrases
Classification: Caution: Substance not yet fully tested.
Safety Phrases:
S22 – Do not breathe dust
S24/25 – Avoid contact with skin and eyes
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
Cite This Product
Idebenone (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-150)
References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/19132784
Alternative Names
2-(10-Hydroxydecyl)-5,6-dimethoxy-3-methyl-1,4-benzoquinone
Research Areas
Cancer, Oxidative Stress
PubChem ID
3686
Scientific Background
Idebenone has been tested for numerous pharmaceutical indications including Alzheimer’s (1), Friedreich’s ataxia (2), and Duchenne muscular dystrophy. It also has similar antioxidant properties to CoQ10, and has therefore been used in anti-aging applications as well (3).
References
1. Gutzmann H., Kuhl K.P., Hadler D and Rapp M.A. (2002) Pharmacopsychiatry. 35(1): 12-18.
2. Di Prospero N.A., Baker A., Jeffries N, Fischbeck K.H. (2007) Lancet Neuro. 6(10): 878-886.
3. McDaniel D., Neudecker B., Dinardo J, Lewis J., Maibach H. (2005) Cosmet Dermatol. 4(3): 167-173.
Quinone antioxidant
Safety Phrases:
S22 – Do not breathe dust
S24/25 – Avoid contact with skin and eyes
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
2. Di Prospero N.A., Baker A., Jeffries N, Fischbeck K.H. (2007) Lancet Neuro. 6(10): 878-886.
3. McDaniel D., Neudecker B., Dinardo J, Lewis J., Maibach H. (2005) Cosmet Dermatol. 4(3): 167-173.