ML167

ML167__Clk4 kinase inhibitor Tebipenem pivoxil

Product Name	ML167
Description	Clk4 kinase inhibitor
Purity	>98% (HPLC)
CAS No.	1285702-20-6
Molecular Formula	C19H17N3O3
Molecular Weight	335.4

Storage Temperature	-20ºC
Shipping Temperature	Shipped Ambient
Product Type	Inhibitor
Solubility	Soluble in DMSO 10 mg/ml, clear
Source	Synthetic
Appearance	Off-white to gray to brown
SMILES	CC1=CC=C(O1)CNC2=NC=NC3=C2C=C(C=C3)C4=CC=C(O4)CO
InChI	InChI=1S/C19H17N3O3/c1-12-3-8-18(24-12)22(2)19-15-9-13(4-6-16(15)20-11-21-19)17-7-5-14(10-23)25-17/h3-9,11,23H,10H2,1-2H3
InChIKey	STBPLRTXXJJXLR-UHFFFAOYSA-N
Safety Phrases	Classification: Acute toxicity, Oral (Category 4), H302 Safety Phrases: S22 – Do not breathe dust. S24/25 – Avoid contact with skin and eyes. S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection. Hazard statements: H302 Harmful if swallowed. Precautionary statements: P264 Wash skin thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P301 + P312 IF SWALLOWED: Call a POISON CENTER or doctor/ physician if you feel unwell. P330 Rinse mouth. P501 Dispose of contents/ container to an approved waste disposal plant.
Cite This Product	ml167 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-505)

Alternative Names	ml-167, 5-4-(5-Methyl-2-furanyl)methylamino-6-quinazolinyl-2-furanmethanol, CID 44968231, NCGC00188654
Research Areas	Cancer, Apoptosis, Cancer Growth Inhibitors, Cell Signaling, Tyrosine Kinase Inhibitors
PubChem ID	51347463
Scientific Background	ml167 is a highly selective inhibitor of Cdc2-like kinase 4 (Clk4). The Cdc2-like kinases are involved in regulation of gene splicing.
References	1. Rosenthal A.S., et al. (2010). In Probe Reports from the NIH Molecular Libraries Program. Bethesda (MD): National Center for Biotechnology Information (US).