Minoxidil

Minoxidil__K+ channel activator MLN4925 (hydrochloride)

Product Name Minoxidil
Description

K+ channel activator

Purity >98%
CAS No. 38304-91-5
Molecular Formula C9H15N5O
Molecular Weight 209.25
Storage Temperature -20ºC
Shipping Temperature Shipped Ambient
Product Type Activator
Solubility Soluble to 25 mM in ethanol and to 25 mM in DMSO
Source Synthetic
Appearance White solid
SMILES C1CCN(CC1)C2=NC(=N+(C(=C2)N)O-)N
InChI InChI=1S/C9H15N5O/c10-7-6-8(12-9(11)14(7)15)13-4-2-1-3-5-13/h6,11,15H,1-5,10H2
InChIKey ZIMGGGWCDYVHOY-UHFFFAOYSA-N
Safety Phrases Classification: Harmful. May be harmful if inhaled, swallowed, or absorbed through the skin.
Safety Phrases:
S22 – Do not breathe dust
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
S24/25- Avoid contact with shin and eyes
Risk Phrases:
R62 – Possible risk of impaired fertility
Hazard Phrases:
H302-H315-H319-H335
Precautionary Phrases:
P261-P305 + P351 + P338
Cite This Product Minoxidil (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-318)
Alternative Names 3-hydroxy-2-imino-6-piperidin-1-ylpyrimidin-4-amine
Research Areas Ion Channels, Neuroscience
PubChem ID 4201
Scientific Background Mioxidil is an anti-hypertensive vasodilator, causing the widening of blood vessels and opening potassium channels (1). It also claims to slow hair loss, most likely having something to do with its nitric oxide chemical moiety (2).
References 1. www.medicinenet.com/minoxidiloral/article.htm
2. Olsen E.A., et al. (2007) J Am Acad Dermatol. 57(5): 767.