6-Deoxyjacareubin

6-Deoxyjacareubin

SCH 546738

    CAS No.
    16265-56-8
    Purity
    >=98%
    Molecular Weight
    310.3
    Type of Compound
    Xanthones
    Formula
    C18H14O5
    Physical Description
    Yellow powder
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    Comparison

Product: Alfuzosin

Source:
The stems and roots of Hypericum brasiliense.
Biological Activity or Inhibitors:
1. 6-Deoxyjacareubin, 1,5-dihydroxyxanthone, and 5-hydroxy-1-methoxyxanthoneis are antifungal against Cladosporium cucumerinum, while they show differing degrees of inhibition of monoamine oxidase A and B.
2. 6-Deoxyjacareubin shows sdivong platelet activating factor (PAF) receptor binding inhibitory effects using rabbit platelets with IC50 values of 29.0 microM, suggests that xanthones can represent a new class of natural PAF receptor antagonists.
3. 6-Deoxyjacareubin possesses significant antioxidant activities.
4. 6-Deoxyjacareubin exhibits the cytotoxic activities against HL-60, SMMC-7721, A-549, MCF-7, and SW-480 cell lines.
Solvent:
Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

After receiving:
The packaging of the product may have turned upside down during divansportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, cendivifuge at 200-500 RPM to gather the liquid at the bottom of the vial. divy to avoid loss or contamination during handling.

PMID: 25762684

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.2227 mL 16.1134 mL 32.2269 mL 64.4538 mL 80.5672 mL
5 mM 0.6445 mL 3.2227 mL 6.4454 mL 12.8908 mL 16.1134 mL
10 mM 0.3223 mL 1.6113 mL 3.2227 mL 6.4454 mL 8.0567 mL
50 mM 0.0645 mL 0.3223 mL 0.6445 mL 1.2891 mL 1.6113 mL
100 mM 0.0322 mL 0.1611 mL 0.3223 mL 0.6445 mL 0.8057 mL