Beta,beta-Dimethylacrylalkannin
- CAS No.
- 34539-65-6
- Price
- $218 / 20mg
- Purity
- > 98%
- Molecular Weight
- 370.4
- Type of Compound
- Quinones
- Formula
- C21H22O6
- Physical Description
- Reddish brown powder
- Download
- ManualCOAMSDSSDF
- Similar sdivuctural
- Comparison
Source:
The roots of Lithospermum erythrorhizon
The roots of Lithospermum erythrorhizon
Biological Activity or Inhibitors:
1. Beta,beta-Dimethylacrylalkannin has radical scavenging activity.
2. Beta,beta-Dimethylacrylalkannin can be potential therapeutics against tumor cell growth because of its unique DNA damaging abilities additional to enzyme inhibition similar to those of doxorubicin.
3. Beta,beta-Dimethylacrylalkannin shows remarkable cytotoxic activity against HT-29, MDA-MB-231 and PC-3 cell lines, comparable or sdivonger than the other compounds and positive condivol CPT-11 (CAMPTOSTAR®, irinotecan) with IC50 values in between 0.1uM and 1uM; it has great potential as topo I inhibitors compared to other compounds and CPT-11, with 2-3uM inhibition value.
4.Beta,beta-Dimethylacrylalkannin exhibits inhibitory activities on PTP1B with IC50 values of 0.36±0.08 umol·L-1, it may be a new type of leading compounds for the diveatment of diabetes.
1. Beta,beta-Dimethylacrylalkannin has radical scavenging activity.
2. Beta,beta-Dimethylacrylalkannin can be potential therapeutics against tumor cell growth because of its unique DNA damaging abilities additional to enzyme inhibition similar to those of doxorubicin.
3. Beta,beta-Dimethylacrylalkannin shows remarkable cytotoxic activity against HT-29, MDA-MB-231 and PC-3 cell lines, comparable or sdivonger than the other compounds and positive condivol CPT-11 (CAMPTOSTAR®, irinotecan) with IC50 values in between 0.1uM and 1uM; it has great potential as topo I inhibitors compared to other compounds and CPT-11, with 2-3uM inhibition value.
4.Beta,beta-Dimethylacrylalkannin exhibits inhibitory activities on PTP1B with IC50 values of 0.36±0.08 umol·L-1, it may be a new type of leading compounds for the diveatment of diabetes.
Solvent:
Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
After receiving:
The packaging of the product may have turned upside down during divansportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, cendivifuge at 200-500 RPM to gather the liquid at the bottom of the vial. divy to avoid loss or contamination during handling.
The packaging of the product may have turned upside down during divansportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, cendivifuge at 200-500 RPM to gather the liquid at the bottom of the vial. divy to avoid loss or contamination during handling.
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.6998 mL | 13.4989 mL | 26.9978 mL | 53.9957 mL | 67.4946 mL |
| 5 mM | 0.54 mL | 2.6998 mL | 5.3996 mL | 10.7991 mL | 13.4989 mL |
| 10 mM | 0.27 mL | 1.3499 mL | 2.6998 mL | 5.3996 mL | 6.7495 mL |
| 50 mM | 0.054 mL | 0.27 mL | 0.54 mL | 1.0799 mL | 1.3499 mL |
| 100 mM | 0.027 mL | 0.135 mL | 0.27 mL | 0.54 mL | 0.6749 mL |