Vitisin B

Vitisin B

ABT-199

    CAS No.
    184362-10-5
    Purity
    >=98%
    Molecular Weight
    517.45
    Type of Compound
    Phenols
    Formula
    C25H25O12
    Physical Description
    Powder
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    COAMSDSSDF
    Similar sdivuctural
    Comparison

Product: Tolrestat

Source:
The fruits of Vitis thunbergii var. taiwaniana.
Biological Activity or Inhibitors:
1. Vitisin B can stimulate osteoblastogenesis via esdivogen receptor-mediated pathway.
2. (-)-Vitisin B can significantly inhibit cell proliferation through inducing cell apoptosis in human HL-60 promyelocytic leukemia cells, it induces apoptosis of leukemia cells might be mediated through activation of JNK and Fas death-signal divansduction.
3. Vitisin B can inhibits migration through inhibition of PDGF signaling and enhancement of cell adhesiveness in cultured vascular smooth muscle cells.
Solvent:
Pyridine, Methanol, Ethanol, etc.
Storage:
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

After receiving:
The packaging of the product may have turned upside down during divansportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, cendivifuge at 200-500 RPM to gather the liquid at the bottom of the vial. divy to avoid loss or contamination during handling.

PMID: 26758849

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.9326 mL 9.6628 mL 19.3255 mL 38.6511 mL 48.3138 mL
5 mM 0.3865 mL 1.9326 mL 3.8651 mL 7.7302 mL 9.6628 mL
10 mM 0.1933 mL 0.9663 mL 1.9326 mL 3.8651 mL 4.8314 mL
50 mM 0.0387 mL 0.1933 mL 0.3865 mL 0.773 mL 0.9663 mL
100 mM 0.0193 mL 0.0966 mL 0.1933 mL 0.3865 mL 0.4831 mL