Isotropic Sutezolid Description liquid (LC – I) are only associated with small modifications around four kJ mol-1 [23].Table 1. Mouse supplier Clearing [Tc ] and Melting [Tm ] points from the salts 1d-f and 2d-f with [Tf2 N- ] because the counterion extracted from the second cooling cycle from the DSC curves. Salt 1d 1e 1f 2d 2e 2f Clearing Points Tc [ C] 108.eight 131.0 133.0 107.9 132.eight 146.9 Melting Points Tm [ C] 86.1 87.1 82.0 60.0 71.4 76.Table two. Transition temperatures (T), enthalpies ( H) as well as the phase transition on the salts 1d-f and 2d-f obtained from the DSC traces upon cooling with ten C min-1 . Salt 1d T [ C] a 108.eight 86.1 -10.9 131.0 87.1 25.three 133.0 82.0 36.4 107.9 60.0 four.four 132.eight 71.four 28.9 146.9 76.5 46.7 H [kJ mol-1 ] 4.2 15.1 8.7 15.3 four.5 4.four 12.0 9.3 1.8 18.7 8.0 4.0 19.7 6.6 four.7 18.3 15.five Transition Iso C (SmA) LC (SmA) r” Cr” r’ Iso C (SmA) LC (SmA) r” Cr” r’ Iso C (SmA) LC (SmA) r” Cr” r’ Iso C (SmA) LC (SmA) r” Cr” r’ Iso C (SmA) LC (SmA) r” Cr” r’ Iso C (SmA) LC (SmA) r” Cr” r’1e1f2d2e2fa Transitions refer towards the 2nd cooling cycles. Temperatures indicate the onset of every peak. The third transition of 1d on cooling isn’t evaluable resulting from its little height. Abbreviations: Iso, isotropic phase; LC, liquid crystalline phase; SmA, smectic A phase; Cr” and Cr’, crystalline solid-state.Comparing the enthalpy values within the series with each and every other (1d-f and 2d-f), they’re fairly alike for the second transitions, and no trend is visible. For the smaller peaks (initially and third transition), the enthalpy values look to rise, aside from a number of exceptions (worth of very first transition of 1e and third transition of 2e). Normally, the highest enthalpy values are calculated for the second transition of every salt. Considering the fact that you will find 3 relevant exothermic peaks in each DSC trace, it could be assumed that the samples exhibit LC phases or a lot more than a single crystalline phase. The very first transition inside the cooling cycle could be identified because the transition in the isotropic liquid in to the liquid crystalline phase (I – LC) because the second transition in every DSC trace has as well higher enthalpy values to become a transition from a crystalline solid-state to a further crystalline solid-state. The transition enthalpies in the second transitions, ranging from 12 to 19 kJ mol-1 , are smaller than the reference values from a liquid crystalline phase to a crystalline solid-state transition (300 kJ mol-1 ), having said that, they may be considerably greater than the values for transitions from LC to LC or LC to an isotropic liquid (4 kJ mol-1 ) [23]. This indicates that the second transitions can be assigned to a transition from a liquid crystalline phase to a crystalline solid-state (LC – Cr”). The enthalpy of your third transition is smaller sized in comparison to theAppl. Sci. 2021, 11,9 ofsecond transition and led towards the assumption that a transition from a crystalline solid-state to yet another crystalline solid-state (Cr”- Cr’) requires place. The salts had been additional analyzed by POM to recognize and confirm the liquid crystalline phases. Two transitions might be observed throughout the POM evaluation for every salt by heating and cooling the samples at ten C min-1 . The following discussion will concentrate on the cooling events. When cooling the samples in the isotropic liquid, a alter in the dark isotropic liquid phase into a birefringent phase has been observed for just about every salt, whereby the new structure was formed quite slowly more than a wide temperature variety. Moreover, a second structure adjust has been observed when cooling the salts additional, which wa.