Product Name :
BMX-IN-1
Description:
BMX-IN-1 is a selective irreversible BMX inhibitor for prostate cancer. BMX-IN-1 can covalently modifies Cys496. BMX-IN-1 inhibits the proliferation of Tel-BMX-transformed Ba/F3 cells at two digit nanomolar concentrations but requires single digit micromolar concentrations to inhibit the proliferation of prostate cancer cell lines. MK2206, is able to potentiate BMX inhibitor’s antiproliferation efficacy against prostate cancer cells.
CAS:
1431525-23-3
Molecular Weight:
524.59
Formula:
C29H24N4O4S
Chemical Name:
N-{5-[9-(4-methanesulfonamidophenyl)-2-oxo-1H,2H-benzo[h]1,6-naphthyridin-1-yl]-2-methylphenyl}prop-2-enamide
Smiles :
CC1=CC=C(C=C1NC(=O)C=C)N1C2=C(C=CC1=O)C=NC1=CC=C(C=C12)C1C=CC(=CC=1)NS(C)(=O)=O
InChiKey:
SFMJNHNUOVADRW-UHFFFAOYSA-N
InChi :
InChI=1S/C29H24N4O4S/c1-4-27(34)31-26-16-23(12-5-18(26)2)33-28(35)14-9-21-17-30-25-13-8-20(15-24(25)29(21)33)19-6-10-22(11-7-19)32-38(3,36)37/h4-17,32H,1H2,2-3H3,(H,31,34)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Bisphenol A} medchemexpress|{Bisphenol A} Metabolic Enzyme/Protease|{Bisphenol A} Biological Activity|{Bisphenol A} Formula|{Bisphenol A} custom synthesis|{Bisphenol A} Epigenetics}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
BMX-IN-1 is a selective irreversible BMX inhibitor for prostate cancer. BMX-IN-1 can covalently modifies Cys496. BMX-IN-1 inhibits the proliferation of Tel-BMX-transformed Ba/F3 cells at two digit nanomolar concentrations but requires single digit micromolar concentrations to inhibit the proliferation of prostate cancer cell lines. MK2206, is able to potentiate BMX inhibitor’s antiproliferation efficacy against prostate cancer cells.|Product information|CAS Number: 1431525-23-3|Molecular Weight: 524.59|Formula: C29H24N4O4S|Synonym:|BMX kinase inhibitor|N-(2-methyl-5-(9-(4-(methylsulfonamido)phenyl)-2-oxobenzo[h][1,6]naphthyridin-1(2H)-yl)phenyl)acrylamide|Chemical Name: N-{5-[9-(4-methanesulfonamidophenyl)-2-oxo-1H,2H-benzo[h]1,6-naphthyridin-1-yl]-2-methylphenyl}prop-2-enamide|Smiles: CC1=CC=C(C=C1NC(=O)C=C)N1C2=C(C=CC1=O)C=NC1=CC=C(C=C12)C1C=CC(=CC=1)NS(C)(=O)=O|InChiKey: SFMJNHNUOVADRW-UHFFFAOYSA-N|InChi: InChI=1S/C29H24N4O4S/c1-4-27(34)31-26-16-23(12-5-18(26)2)33-28(35)14-9-21-17-30-25-13-8-20(15-24(25)29(21)33)19-6-10-22(11-7-19)32-38(3,36)37/h4-17,32H,1H2,2-3H3,(H,31,34)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Verteporfin} MedChemExpress|{Verteporfin} YAP|{Verteporfin} Technical Information|{Verteporfin} Data Sheet|{Verteporfin} supplier|{Verteporfin} Autophagy} |Shelf Life: ≥12 months if stored properly.PMID:24381199 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|