Product Name :
Roluperidone
Description:
Roluperidone (CYR-101) is a novel cyclic amide derivative that has high equipotent affinities for 5-HT2A and sigma-2 receptors (Ki of 7.53 nM and 8.19 nM for 5-HT2A and sigma-2, respectively).
CAS:
359625-79-9
Molecular Weight:
366.43
Formula:
C22H23FN2O2
Chemical Name:
2-({1-[2-(4-fluorophenyl)-2-oxoethyl]piperidin-4-yl}methyl)-2,3-dihydro-1H-isoindol-1-one
Smiles :
O=C1C2C=CC=CC=2CN1CC1CCN(CC(=O)C2C=CC(F)=CC=2)CC1
InChiKey:
RNRYULFRLCBRQS-UHFFFAOYSA-N
InChi :
InChI=1S/C22H23FN2O2/c23-19-7-5-17(6-8-19)21(26)15-24-11-9-16(10-12-24)13-25-14-18-3-1-2-4-20(18)22(25)27/h1-8,16H,9-15H2
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Abelacimab} medchemexpress|{Abelacimab} Metabolic Enzyme/Protease|{Abelacimab} Biological Activity|{Abelacimab} In Vivo|{Abelacimab} custom synthesis|{Abelacimab} Cancer}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Roluperidone (CYR-101) is a novel cyclic amide derivative that has high equipotent affinities for 5-HT2A and sigma-2 receptors (Ki of 7.53 nM and 8.19 nM for 5-HT2A and sigma-2, respectively).|Product information|CAS Number: 359625-79-9|Molecular Weight: 366.43|Formula: C22H23FN2O2|Chemical Name: 2-({1-[2-(4-fluorophenyl)-2-oxoethyl]piperidin-4-yl}methyl)-2,3-dihydro-1H-isoindol-1-one|Smiles: O=C1C2C=CC=CC=2CN1CC1CCN(CC(=O)C2C=CC(F)=CC=2)CC1|InChiKey: RNRYULFRLCBRQS-UHFFFAOYSA-N|InChi: InChI=1S/C22H23FN2O2/c23-19-7-5-17(6-8-19)21(26)15-24-11-9-16(10-12-24)13-25-14-18-3-1-2-4-20(18)22(25)27/h1-8,16H,9-15H2|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 33.{{DBCO-Biotin} medchemexpress|{DBCO-Biotin} PROTAC Linkers|{DBCO-Biotin} Immunology/Inflammation|{DBCO-Biotin} Protocol|{DBCO-Biotin} In Vitro|{DBCO-Biotin} supplier} 33 mg/mL (90.PMID:23614016 96 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Roluperidone (CYR-101) also shows binding affinity for α1-adrenergic receptors but low or no affinity for muscarinic, cholinergic, and histaminergic receptors. Although Roluperidone (CYR-101) has no affinities for pre- or postsynaptic dopaminergic receptors, it is probable that sigma-2 receptors are implicated in the modulation of dopamine and glutamatergic pathways, as well as in calcium neuronal modulation.|Products are for research use only. Not for human use.|