Product Name :
GPLGIAGQ
Description:
GPLGIAGQ, a MMP2-cleavable polypeptide, is used as a stimulus-sensitive linker in both liposomal and micellar nanocarriers for MMP2-triggered tumor targeting. GPLGIAGQ can be used to synthesis unique MMP2-targeted photosensitizer in photodynamic therapy (PDT).
CAS:
109053-09-0
Molecular Weight:
711.81
Formula:
C31H53N9O10
Chemical Name:
(2S)-2-{2-[(2S)-2-[(2S,3S)-2-{2-[(2S)-2-{[(2S)-1-(2-aminoacetyl)pyrrolidin-2-yl]formamido}-4-methylpentanamido]acetamido}-3-methylpentanamido]propanamido]acetamido}-4-carbamoylbutanoic acid
Smiles :
CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)CN)C(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(O)=O
InChiKey:
BLNMYSBCIVAVFK-PFZXUFBWSA-N
InChi :
InChI=1S/C31H53N9O10/c1-6-17(4)26(30(48)36-18(5)27(45)34-14-23(42)37-19(31(49)50)9-10-22(33)41)39-24(43)15-35-28(46)20(12-16(2)3)38-29(47)21-8-7-11-40(21)25(44)13-32/h16-21,26H,6-15,32H2,1-5H3,(H2,33,41)(H,34,45)(H,35,46)(H,36,48)(H,37,42)(H,38,47)(H,39,43)(H,49,50)/t17-,18-,19-,20-,21-,26-/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
GPLGIAGQ, a MMP2-cleavable polypeptide, is used as a stimulus-sensitive linker in both liposomal and micellar nanocarriers for MMP2-triggered tumor targeting. GPLGIAGQ can be used to synthesis unique MMP2-targeted photosensitizer in photodynamic therapy (PDT).|Product information|CAS Number: 109053-09-0|Molecular Weight: 711.81|Formula: C31H53N9O10|Chemical Name: (2S)-2-{2-[(2S)-2-[(2S,3S)-2-{2-[(2S)-2-{[(2S)-1-(2-aminoacetyl)pyrrolidin-2-yl]formamido}-4-methylpentanamido]acetamido}-3-methylpentanamido]propanamido]acetamido}-4-carbamoylbutanoic acid|Smiles: CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)CN)C(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(O)=O|InChiKey: BLNMYSBCIVAVFK-PFZXUFBWSA-N|InChi: InChI=1S/C31H53N9O10/c1-6-17(4)26(30(48)36-18(5)27(45)34-14-23(42)37-19(31(49)50)9-10-22(33)41)39-24(43)15-35-28(46)20(12-16(2)3)38-29(47)21-8-7-11-40(21)25(44)13-32/h16-21,26H,6-15,32H2,1-5H3,(H2,33,41)(H,34,45)(H,35,46)(H,36,48)(H,37,42)(H,38,47)(H,39,43)(H,49,50)/t17-,18-,19-,20-,21-,26-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Bardoxolone} medchemexpress|{Bardoxolone} Necroptosis|{Bardoxolone} Protocol|{Bardoxolone} In Vitro|{Bardoxolone} manufacturer|{Bardoxolone} Cancer} |Shelf Life: ≥12 months if stored properly.{{Fmoc-Ser(tBu)-OH} medchemexpress|{Fmoc-Ser(tBu)-OH} {Amino Acid Derivatives}|{Fmoc-Ser(tBu)-OH} Activator|{Fmoc-Ser(tBu)-OH} Protocol|{Fmoc-Ser(tBu)-OH} Formula|{Fmoc-Ser(tBu)-OH} supplier} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:32490699 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|GPLGIAGQ is used to trigger PEG deshielding of liposomal carriers, resulting in enhanced cellular internalization.|Products are for research use only. Not for human use.|