Product Name :
Rabbit anti-YOD1 Polyclonal Antibody(C-term)
Synonym :
Ubiquitin thioesterase OTU1; DUBA-8; HIV-1-induced protease 7; HIN-7; HsHIN7; OTU domain-containing protein 2; YOD1; DUBA8; HIN7; OTUD2
Host :
Rabbit
Species Reactivity:
Human
Specificity :
This YOD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 319-347 amino acids from the C-terminal region of human YOD1.
Predicted Reactivity:
Chicken, Zebrafish
Applications :
WB~~1:1000IHC-P~~1:50~100IF~~1:10~50
Immunogen:
Concentration :
Purification :
Clonality:
Polyclonal Antibody
Storage Temp.:
Maintain refrigerated at 2-8 ° C for up to 2 weeksFor long term storage store at -20 ° C in small aliquots to prevent free that cycles
Research areas :
Cell Biology;Signal Transduction
Background :
Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by triming the ubiquitin chain on the associated substrate to facilitate their threading through the VCP/p97 pore. Ubiquitin moieties on substrates may present a steric impediment to the threading process when the substrate is transferred to the VCP pore and threaded through VCP’s axial channel. Mediates deubiquitination of ‘Lys-27’-, ‘Lys-29’- and ‘Lys-33’-linked polyubiquitin chains. Also able to hydrolyze ‘Lys-11’-linked ubiquitin chains. Cleaves both polyubiquitin and di-ubiquitin.
UniProt :
Q5VVQ6
Additional information:
Product Details FAQ Citations(0) Video Pictures Documents |Overview |Description Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab) |Synonym Ubiquitin thioesterase OTU1; DUBA-8; HIV-1-induced protease 7; HIN-7; HsHIN7; OTU domain-containing protein 2; YOD1; DUBA8; HIN7; OTUD2 |Host Rabbit |Specificity This YOD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 319-347 amino acids from the C-terminal region of human YOD1. |Species Reactivity Human |Predicted Reactivity Chicken, Zebrafish |Applications WB~~1:1000IHC-P~~1:50~100IF~~1:10~50 |Properties |Clonality Polyclonal Antibody |Isotype Rabbit Ig |Storage Temp. Maintain refrigerated at 2-8 ° C for up to 2 weeksFor long term storage store at -20 ° C in small aliquots to prevent free that cycles |Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |Research areas Cell Biology;Signal Transduction |Target |Background Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by triming the ubiquitin chain on the associated substrate to facilitate their threading through the VCP/p97 pore. Ubiquitin moieties on substrates may present a steric impediment to the threading process when the substrate is transferred to the VCP pore and threaded through VCP’s axial channel. Mediates deubiquitination of ‘Lys-27’-, ‘Lys-29’- and ‘Lys-33’-linked polyubiquitin chains. Also able to hydrolyze ‘Lys-11’-linked ubiquitin chains. Cleaves both polyubiquitin and di-ubiquitin. |UniProt Q5VVQ6 |References |References Ernst, R., et al. Mol. Cell 36(1):28-38(2009) |Tips:This product is for research use only. Not for use in diagnostic prodcedures.
Rabbit anti-YOD1 Polyclonal Antibody(C-term)
Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.Related websites: https://www.medchemexpress.com/antibodies.html
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