Product Name :
DBCO-PEG1-NHS ester
Description:
DBCO-PEG1-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
CAS:
2228857-34-7
Molecular Weight:
517.53
Formula:
C28H27N3O7
Chemical Name:
2,5-dioxopyrrolidin-1-yl 3-[2-(4-{2-azatricyclo[10.4.0.0⁴,⁹]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl}-4-oxobutanamido)ethoxy]propanoate
Smiles :
O=C(CCC(=O)NCCOCCC(=O)ON1C(=O)CCC1=O)N1CC2=CC=CC=C2C#CC2=CC=CC=C12
InChiKey:
TYDZSBPFYBWRTP-UHFFFAOYSA-N
InChi :
InChI=1S/C28H27N3O7/c32-24(29-16-18-37-17-15-28(36)38-31-26(34)13-14-27(31)35)11-12-25(33)30-19-22-7-2-1-5-20(22)9-10-21-6-3-4-8-23(21)30/h1-8H,11-19H2,(H,29,32)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
DBCO-PEG1-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.|Product information|CAS Number: 2228857-34-7|Molecular Weight: 517.53|Formula: C28H27N3O7|Chemical Name: 2,5-dioxopyrrolidin-1-yl 3-[2-(4-{2-azatricyclo[10.{{Asciminib} medchemexpress|{Asciminib} Bcr-Abl|{Asciminib} Purity & Documentation|{Asciminib} Data Sheet|{Asciminib} custom synthesis|{Asciminib} Autophagy} 4.0.0⁴,⁹]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl}-4-oxobutanamido)ethoxy]propanoate|Smiles: O=C(CCC(=O)NCCOCCC(=O)ON1C(=O)CCC1=O)N1CC2=CC=CC=C2C#CC2=CC=CC=C12|InChiKey: TYDZSBPFYBWRTP-UHFFFAOYSA-N|InChi: InChI=1S/C28H27N3O7/c32-24(29-16-18-37-17-15-28(36)38-31-26(34)13-14-27(31)35)11-12-25(33)30-19-22-7-2-1-5-20(22)9-10-21-6-3-4-8-23(21)30/h1-8H,11-19H2,(H,29,32)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Diclofenac} web|{Diclofenac} Apoptosis|{Diclofenac} Purity & Documentation|{Diclofenac} In Vitro|{Diclofenac} manufacturer|{Diclofenac} Autophagy} |Shelf Life: ≥12 months if stored properly.PMID:23907051 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|