Product Name :
Propiverine hydrochloride
Description:
Propiverine is an anticholinergic drug used for the treatment of overactive bladder and urinary incontinence. Propiverine is a muscarinic receptor antagonist possessing additional properties, i.e., block of L-type Ca2+ channels.
CAS:
54556-98-8
Molecular Weight:
403.94
Formula:
C23H30ClNO3
Chemical Name:
1-methylpiperidin-4-yl 2,2-diphenyl-2-propoxyacetate hydrochloride
Smiles :
Cl.CCCOC(C(=O)OC1CCN(C)CC1)(C1=CC=CC=C1)C1=CC=CC=C1
InChiKey:
KFUJMHHNLGCTIJ-UHFFFAOYSA-N
InChi :
InChI=1S/C23H29NO3.ClH/c1-3-18-26-23(19-10-6-4-7-11-19,20-12-8-5-9-13-20)22(25)27-21-14-16-24(2)17-15-21;/h4-13,21H,3,14-18H2,1-2H3;1H
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Propiverine is an anticholinergic drug used for the treatment of overactive bladder and urinary incontinence. Propiverine is a muscarinic receptor antagonist possessing additional properties, i.e., block of L-type Ca2+ channels.|Product information|CAS Number: 54556-98-8|Molecular Weight: 403.94|Formula: C23H30ClNO3|Chemical Name: 1-methylpiperidin-4-yl 2,2-diphenyl-2-propoxyacetate hydrochloride|Smiles: Cl.CCCOC(C(=O)OC1CCN(C)CC1)(C1=CC=CC=C1)C1=CC=CC=C1|InChiKey: KFUJMHHNLGCTIJ-UHFFFAOYSA-N|InChi: InChI=1S/C23H29NO3.ClH/c1-3-18-26-23(19-10-6-4-7-11-19,20-12-8-5-9-13-20)22(25)27-21-14-16-24(2)17-15-21;/h4-13,21H,3,14-18H2,1-2H3;1H|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: Solubility (25°C).{{Evolocumab} medchemexpress|{Evolocumab} NF-κB|{Evolocumab} Technical Information|{Evolocumab} In Vitro|{Evolocumab} custom synthesis|{Evolocumab} Cancer} 80 mg/mL(198.{{L-Carnosine} site|{L-Carnosine} Endogenous Metabolite|{L-Carnosine} Technical Information|{L-Carnosine} In Vitro|{L-Carnosine} custom synthesis|{L-Carnosine} Epigenetic Reader Domain} 04 mM).PMID:35901518 |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vivo:|Propiverine administered orally in mice binds significantly to muscarinic receptors in the bladder and its binding activity is more prominent and longer-lasting in the bladder than in the submaxillary gland. Propiverine is well absorbed from the gastrointestinal tract and undergoes high first-pass metabolism. It is metabolized in the liver and intestine to form the active metabolites.|Products are for research use only. Not for human use.|