Product Name :
CID 1375606
Description:
CID 1375606 is an agonist of GPR27 SREB1 that induces coupling of the receptor to arrestin 2
CAS:
313493-80-0
Molecular Weight:
385.24
Formula:
C20H14Cl2N2O2
Chemical Name:
2,4-Dichloro-N-(phenylcarbamoyl)phenylbenzamide
Smiles :
O=C(C1=CC=C(Cl)C=C1Cl)N(C1C=CC=CC=1)C(=O)NC1C=CC=CC=1
InChiKey:
ZQAVKJQEPSJXHB-UHFFFAOYSA-N
InChi :
InChI=1S/C20H14Cl2N2O2/c21-14-11-12-17(18(22)13-14)19(25)24(16-9-5-2-6-10-16)20(26)23-15-7-3-1-4-8-15/h1-13H,(H,23,26)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Polymyxin B} web|{Polymyxin B} Anti-infection|{Polymyxin B} Technical Information|{Polymyxin B} Description|{Polymyxin B} supplier|{Polymyxin B} Epigenetic Reader Domain}
Shelf Life:
≥360 days if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
CID 1375606 is an agonist of GPR27 SREB1 that induces coupling of the receptor to arrestin 2|Product information|CAS Number: 313493-80-0|Molecular Weight: 385.{{Clobetasol propionate} web|{Clobetasol propionate} Cytochrome P450|{Clobetasol propionate} NF-κB|{Clobetasol propionate} Biological Activity|{Clobetasol propionate} In Vivo|{Clobetasol propionate} custom synthesis} 24|Formula: C20H14Cl2N2O2|Chemical Name: 2,4-Dichloro-N-(phenylcarbamoyl)phenylbenzamide|Smiles: O=C(C1=CC=C(Cl)C=C1Cl)N(C1C=CC=CC=1)C(=O)NC1C=CC=CC=1|InChiKey: ZQAVKJQEPSJXHB-UHFFFAOYSA-N|InChi: InChI=1S/C20H14Cl2N2O2/c21-14-11-12-17(18(22)13-14)19(25)24(16-9-5-2-6-10-16)20(26)23-15-7-3-1-4-8-15/h1-13H,(H,23,26)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO: 77 mg/mL(199.PMID:24268253 87 mM). Water: Insoluble.|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|CID 1375606 is a GPR27-specific surrogate agonist. GPR27 is characterized by a high level of conservation among vertebrates and a predominant expression in the central nervous system. In addition, it has recently been linked to insulin secretion[1].|References:|Dupuis N, et al. Activation of the Orphan G Protein-Coupled Receptor GPR27 by Surrogate Ligands Promotes β-Arrestin 2 Recruitment. Mol Pharmacol. 2017 Jun;91(6):595-608.Products are for research use only. Not for human use.|