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TRAIL-R1 (human) monoclonal antibody (DJR1)
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DR4 is 56kDa member 10A of the TNFR superfamily (TNFRSF10A), also known as TRAIL-R1, Apo-2, and CD261.3025082-14-5 Protocol It is expressed at low levels by activated T cells and some tumors. After TRAIL engagement, DR4 (TRAIL-R1), through activation of NF-κB, induces apoptosis in the TRAIL ligated cell.
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| Alternative Name TRAIL receptor 1, Apo-2, CD261, DR4, Death receptor 4, TNFRSF 10A, TNF-related apoptosis-inducing ligand receptor 1, Tumor necrosis factor receptor superfamily member 10A | Application Flow Cytometry, WB | Clone DJR1 | Formulation Liquid.1353485-38-7 Data Sheet In PBS, pH 7.PMID:30969537 2, containing 0.09% sodium azide. | GenBank ID U90875 | Gene/Protein Identifier 8798 (Entrez GeneID) | Host Mouse | Immunogen Recombinant human TRAIL-R1 extracellular domain IgG1 Fc fusion protein. | Isotype IgG1 | Species Reactivity Human | UniProt ID O00220 | Unit of Measure (UM) µg