AG1296__PDGFR kinase inhibitor Pexidartinib
Product Name
AG1296
Description
PDGFR kinase inhibitor
Purity
>98% (TLC)
CAS No.
146535-11-7
Molecular Formula
C16H14N2O2
Molecular Weight
266.3
Storage Temperature
-20ºC
Shipping Temperature
Shipped Ambient
Product Type
Inhibitor
Solubility
Soluble in DMSO or dichloromethane
Source
Synthetic
Appearance
Off-white to brownish solid
SMILES
C1=C(OC)C(=CC2=NC=C(N=C12)C3=CC=CC=C3)OC
InChI
InChI=1S/C16H14N2O2/c1-19-15-8-12-13(9-16(15)20-2)18-14(10-17-12)11-6-4-3-5-7-11/h3-10H,1-2H3
InChIKey
QNOXYUNHIGOWNY-UHFFFAOYSA-N
Safety Phrases
Classification:
Not a hazardous substance or mixture.
Safety Phrases:
S22 – Do not breathe dust.
S24/25 – Avoid contact with skin and eyes.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.
Cite This Product
AG1296 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-426)
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/19112107
Alternative Names
Tyrphostin AG 1296, 6,7-Dimethoxy-3-phenylquinoxaline, 6,7-Dimethoxy-2-phenylquinoxaline
Research Areas
Cancer, Apoptosis, Cancer Growth Inhibitors, Cell Signaling, Tyrosine Kinase Inhibitors
PubChem ID
2049
Scientific Background
AG-1296 is a potent and specific inhibitor of PDGF receptor tyrosine kinase. AG-1296 is cell-permeable.
References
1. Strutz F., et al. (2001) Kidney Int. 59(2): 579–592.
PDGFR kinase inhibitor
Not a hazardous substance or mixture.
Safety Phrases:
S22 – Do not breathe dust.
S24/25 – Avoid contact with skin and eyes.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.