CPD5__MPS1/TTK Inhibitor AZD2014
Product Name
CPD5
Description
MPS1/TTK Inhibitor
Purity
99.1%
Molecular Formula
C33H40N8O2
Molecular Weight
580.74
Storage Temperature
-20ºC
Shipping Temperature
Blue Ice or 4ºC
Product Type
Inhibitor
Solubility
Soluble in CDCI3
Source
Synthetic
Appearance
Yellow Solid
SMILES
COC1=CC(N2CCN(C)CC2)=CC=C1N C3=NC=C(CCC4=C5N(C)N=C4C(NC 6=C(CC)C=CC=C6CC)=O)C5=N3
InChI
InChI=1S/C12H19N3O/c1-14-5-7-15(8-6-14)10-3-4-11(13)12(9-10)16-2/h3-4,9H,5-8,13H2,1-2H3
InChIKey
LUYPGLRYFIVYTH-UHFFFAOYSA-N
Safety Phrases
Classification: Caution: Substance not yet fully tested.
Safety Phrases:
S22 – Do not breathe dust
S24/25 – Avoid contact with skin and eyes
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
Cite This Product
CPD5 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-183)
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/19119428
Alternative Names
N-(2,6-diethylphenyl)-8-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)-1-methyl-4,5-dihydro-1H-pyrazolo4,3-hquinazoline-3-carboxamide
Research Areas
Cancer, Cell Signaling
Scientific Background
This is a protein kinase inhibitor with activity against MPS1/TTK. It has an IC50 of 0.10 µM in cellular proliferation inhibition assay using A2780 cells.
References
1. Caldarelli, M., et al. (2011) Bioorganic & Medicinal Chemistry Letters 21.15: 4507-4511.
MPS1/TTK Inhibitor
Safety Phrases:
S22 – Do not breathe dust
S24/25 – Avoid contact with skin and eyes
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection