Cycloheximide__Translation inhibitor Verteporfin
Product Name
Cycloheximide
Description
Translation inhibitor
Purity
>98%
CAS No.
66-81-9
Molecular Formula
C15H23NO4
Molecular Weight
281.35
Storage Temperature
-20ºC
Shipping Temperature
Shipped Ambient
Product Type
Inhibitor
Solubility
Soluble to 50 mM in Ethanol and 25 mM in water
Source
Synthetic
Appearance
White solid
SMILES
Cemail protected1CC@@H(C(=O)C@@H(C1)C@@H(CC2CC(=O)NC(=O)C2)O)C
InChI
InChI=1S/C15H23NO4/c1-8-3-9(2)15(20)11(4-8)12(17)5-10-6-13(18)16-14(19)7-10/h8-12,17H,3-7H2,1-2H3,(H,16,18,19)/t8-,9-,11-,12
InChIKey
YPHMISFOHDHNIV-FSZOTQKASA-N
Safety Phrases
Classification: Very toxic. May be fatal if inhaled, swallowed or absorbed through skin.
Safety Phrases:
S22 – Do not breathe dust
S24/25 – Avoid contact with skin and eyes
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
S45 – In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible)
Risk Phrases:
R26/27/28 – Very Toxic by inhalation, in contact with skin and if swallowed
R62 – Possible risk of impaired fertility
R68- Possible risk of irreversible effects
Hazard Phrases:
H300-H341-H360D-H411
Precautionary Phrases:
P201-P264-P273-P281-P301 + P310-P308 + P313
Cite This Product
Cycloheximide (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-247)
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/19120021
Alternative Names
4-{(2R)-2-(1S,3S,5S)-3,5-Dimethyl-2-oxocyclohexyl-2-hydroxyethyl}-2,6-piperidinedione
Research Areas
Cancer, Apoptosis
PubChem ID
6197
Scientific Background
Selective inhibitor of eukaryotic protein synthesis blocking tRNA binding and release from ribosomes. Induces apoptosis in a variety of transformed and normal cell lines, including T-cells.
References
1. Obrig T.G., et al. (1971) J Biol Chem. 246:174.
Translation inhibitor
Safety Phrases:
S22 – Do not breathe dust
S24/25 – Avoid contact with skin and eyes
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
S45 – In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible)
Risk Phrases:
R26/27/28 – Very Toxic by inhalation, in contact with skin and if swallowed
R62 – Possible risk of impaired fertility
R68- Possible risk of irreversible effects
Hazard Phrases:
H300-H341-H360D-H411
Precautionary Phrases:
P201-P264-P273-P281-P301 + P310-P308 + P313