GDC 0941__pan-PI3K kinase inhibitor Elamipretide
Product Name
GDC 0941
Description
pan-PI3K kinase inhibitor
Purity
>98%
CAS No.
957054-30-7
Molecular Formula
C23H27N7O3S2
Molecular Weight
513.63
Storage Temperature
-20ºC
Shipping Temperature
Shipped Ambient
Product Type
Inhibitor
Solubility
Soluble in DMSO
Source
Synthetic
Appearance
White solid
SMILES
CS(=O)(=O)N1CCN(CC1)CC2=CC3=C(S2)C(=NC(=N3)C4=C5C=NNC5=CC=C4)N6CCOCC6
InChI
InChI=1S/C23H27N7O3S2/c1-35(31,32)30-7-5-28(6-8-30)15-16-13-20-21(34-16)23(29-9-11-33-12-10-29)26-22(25-20)17-3-2-4-19-18(17)14-24-27-19/h2-4,13-14H,5-12,15H2,1H3,(H,24,27)
InChIKey
LHNIIDJUOCFXAP-UHFFFAOYSA-N
Safety Phrases
Classification:
Not a hazardous substance or mixture.
Safety Phrases:
S22 – Do not breathe dust.
S24/25 – Avoid contact with skin and eyes.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.
Cite This Product
GDC 0941 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-501)
References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/19125169
Alternative Names
Pictrelisib, Pictilisib, GNE 0941, 2-(1H-indazol-4-yl)-6-4-(methylsulfonyl)-1-piperazinylmethyl-4-(4-morpholinyl)-thieno3,2-dpyrimidine
Research Areas
Cancer, Apoptosis, Cancer Growth Inhibitors, Cell Signaling, Tyrosine Kinase Inhibitors
PubChem ID
17755052
Scientific Background
GDC 0941 is a potent inhibitor of the PI 3-kinase family. Specifically, GDC 0941 has been shown to inhibit PI3Kα, PI3Kβ, PI3Kδ and PI3Kγ.
References
1. Zheng J., Wang H., Yao J., & Zou X. (2014) Die Pharmazie. 69(1): 38–42.
pan-PI3K kinase inhibitor
Not a hazardous substance or mixture.
Safety Phrases:
S22 – Do not breathe dust.
S24/25 – Avoid contact with skin and eyes.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.