Kainic acid__Kainate agonist PF-4136310
Product Name
Kainic acid
Description
Kainate agonist
Purity
>99% (HPLC)
CAS No.
58002-62-3
Molecular Formula
C10H15NO4•H2O
Molecular Weight
213.2
Storage Temperature
-20ºC
Shipping Temperature
Shipped Ambient
Product Type
Agonist
Solubility
May be dissolved in water (10 mg/ml)
Source
Synthetic
Appearance
White powder
SMILES
CC(=C)email protected1CNC@@H(email protected1CC(=O)O)C(=O)O
InChI
InChI=1S/C10H15NO4/c1-5(2)7-4-11-9(10(14)15)6(7)3-8(12)13/h6-7,9,11H,1,3-4H2,2H3,(H,12,13)(H,14,15)/t6-,7+,9-/m0/s1
InChIKey
VLSMHEGGTFMBBZ-OOZYFLPDSA-N
Safety Phrases
Classification: Caution: Substance not yet fully tested.
Safety Phrases:
S22 – Do not breathe dust.
S24/25 – Avoid contact with skin and eyes
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
Cite This Product
Kainic acid (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-364)
Alternative Names
(2S,3S,4S)-3-(carboxymethyl)-4-(prop-1-en-2-yl)-pyrrolidine-2-carboxylic acid, Monohydrate
Research Areas
Glutamate Receptors, Ion Channels, Kainate Receptors, Neuroscience, Neurotransmitter Receptors
PubChem ID
10255
Scientific Background
Kainic acid is a conformationally restricted glutamate analog which acts as a selective agonist at kainate receptors. It is a central nervous system stimulant and neurotoxin. It acts as a classic neuroexcitatory agent for induction of seizures in laboratory animals (typical dose 10-30 mg/kg).
References
1. Watkins J.C., et al. (1981) Ann. Rev. Pharmacol. Toxicol. 21: 165.
Kainate agonist
Safety Phrases:
S22 – Do not breathe dust.
S24/25 – Avoid contact with skin and eyes
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection