Lovastatin__HMG-CoA reductase inhibitor Calicheamicin
Product Name
Lovastatin
Description
HMG-CoA reductase inhibitor
Purity
>98%
CAS No.
75330-75-5
Molecular Formula
C24H36O5
Molecular Weight
404.54
Storage Temperature
-20ºC
Shipping Temperature
Shipped Ambient
Product Type
Inhibitor
Solubility
Soluble to 50 mM in ethanol and 100 mM in DMSO
Source
Synthetic
Appearance
White solid
SMILES
CCemail protected(C)C(=O)Oemail protected1Cemail protected(C=C2email protected1email protected(email protected(C=C2)C)CCC@@H3Cemail protected(CC(=O)O3)O)C
InChI
InChI=1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18
InChIKey
PCZOHLXUXFIOCF-BXMDZJJMSA-N
Safety Phrases
Classification: Harmful. May be harmful if inhaled, swallowed, or absorbed through skin.
Safety Phrases:
S22 – Do not breathe dust
S24/25 – Avoid contact with skin and eyes
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
Risk Phrases:
R62- Possible risk of impaired fertility
Cite This Product
Lovastatin (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-256)
Alternative Names
(1S,3R,7S,8S,8aR)-8-{2-(2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-ylethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-1-naphthalenyl (2S)-2-methylbutanoate, Mevinolin
Research Areas
Cancer, Apoptosis
PubChem ID
53232
Scientific Background
Lovastatin is a member of the drug class of statins, used for lowering cholersterol, thereby preventing cardiovascular disease. They have a powerful inhibitory effect on HMG-CoA reducatse (1).
References
1. Alberts A.W. (1998) Am J Cardio. 62(15): 10J-15J.
HMG-CoA reductase inhibitor
Safety Phrases:
S22 – Do not breathe dust
S24/25 – Avoid contact with skin and eyes
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection
Risk Phrases:
R62- Possible risk of impaired fertility