All transitions encountered during each trajectory. Additionally, the computation times we observed are also stored in this file. It is often impossible to measure precisely the computation time of a single decision. This is why only the computation time of each purchase Ixazomib citrate trajectory is reported in this file. 5. Our results are exported. After each Disitertide custom synthesis experiment has been performed, a set of K result files is obtained. We need to provide all agent files and result files to export the data. ./BBRL-export –agent \ –agent_file \ –experiment \ –experiment file \ … –agent \ –agent_file \PLOS ONE | DOI:10.1371/journal.pone.0157088 June 15,7 /Benchmarking for Bayesian Reinforcement Learning–experiment \ –experiment_file BBRL will sort the data automatically and produce several files for each experiment. ?A graph comparing offline computation cost w.r.t. performance; ?A graph comparing online computation cost w.r.t. performance; ?A graph where the X-axis represents the offline time bound, while the Y-axis represents the online time bound. A point of the space corresponds to set of bounds. An algorithm is associated to a point of the space if its best agent, satisfying the constraints, is among the best ones when compared to the others; ?A table reporting the results of each agent. BBRL will also produce a report file in LATEX gathering the 3 graphs and the table for each experiment. More than 2.000 commands have to be entered in order to reproduce the results of this paper. We decided to provide several Lua script in order to simplify the process. By completing some configuration files, which are illustrated by Figs 1 and 2, the user can define the agents, the possible values of their parameters and the experiments to conduct. Those configuration files are then used by a script called make_scripts.sh, included within the library, whose purpose is to generate four other scripts: ?0-init.sh Create the experiment files, and create the formulas sets required by OPPS agents. ?1-ol.sh Create the agents and train them on the prior distribution(s).Fig 1. Example of a configuration file for the agents. doi:10.1371/journal.pone.0157088.gPLOS ONE | DOI:10.1371/journal.pone.0157088 June 15,8 /Benchmarking for Bayesian Reinforcement LearningFig 2. Example of a configuration file for the experiments. doi:10.1371/journal.pone.0157088.g?2-re.sh Run all the experiments. ?3-export.sh Generate the LATEX reports. Due to the high computation power required, we made those scripts compatible with workload managers such as SLURM. In this case, each cluster should provide the same amount of CPU power in order to get consistent time measurements. To sum up, when the configuration files are completed correctly, one can start the whole process by executing the four scripts, and retrieve the results in nice LATEX reports. It is worth noting that there is no computation budget given to the agents. This is due to the diversity of the algorithms implemented. No algorithm is “anytime” natively, in the sense that we cannot stop the computation at any time and receive an answer from the agent instantly. Strictly speaking, it is possible to develop an anytime version of some of the algorithms considered in BBRL. However, we made the choice to stay as close as possible to the original algorithms proposed in their respective papers for reasons of fairness. In consequence, although computation time is a.All transitions encountered during each trajectory. Additionally, the computation times we observed are also stored in this file. It is often impossible to measure precisely the computation time of a single decision. This is why only the computation time of each trajectory is reported in this file. 5. Our results are exported. After each experiment has been performed, a set of K result files is obtained. We need to provide all agent files and result files to export the data. ./BBRL-export –agent \ –agent_file \ –experiment \ –experiment file \ … –agent \ –agent_file \PLOS ONE | DOI:10.1371/journal.pone.0157088 June 15,7 /Benchmarking for Bayesian Reinforcement Learning–experiment \ –experiment_file BBRL will sort the data automatically and produce several files for each experiment. ?A graph comparing offline computation cost w.r.t. performance; ?A graph comparing online computation cost w.r.t. performance; ?A graph where the X-axis represents the offline time bound, while the Y-axis represents the online time bound. A point of the space corresponds to set of bounds. An algorithm is associated to a point of the space if its best agent, satisfying the constraints, is among the best ones when compared to the others; ?A table reporting the results of each agent. BBRL will also produce a report file in LATEX gathering the 3 graphs and the table for each experiment. More than 2.000 commands have to be entered in order to reproduce the results of this paper. We decided to provide several Lua script in order to simplify the process. By completing some configuration files, which are illustrated by Figs 1 and 2, the user can define the agents, the possible values of their parameters and the experiments to conduct. Those configuration files are then used by a script called make_scripts.sh, included within the library, whose purpose is to generate four other scripts: ?0-init.sh Create the experiment files, and create the formulas sets required by OPPS agents. ?1-ol.sh Create the agents and train them on the prior distribution(s).Fig 1. Example of a configuration file for the agents. doi:10.1371/journal.pone.0157088.gPLOS ONE | DOI:10.1371/journal.pone.0157088 June 15,8 /Benchmarking for Bayesian Reinforcement LearningFig 2. Example of a configuration file for the experiments. doi:10.1371/journal.pone.0157088.g?2-re.sh Run all the experiments. ?3-export.sh Generate the LATEX reports. Due to the high computation power required, we made those scripts compatible with workload managers such as SLURM. In this case, each cluster should provide the same amount of CPU power in order to get consistent time measurements. To sum up, when the configuration files are completed correctly, one can start the whole process by executing the four scripts, and retrieve the results in nice LATEX reports. It is worth noting that there is no computation budget given to the agents. This is due to the diversity of the algorithms implemented. No algorithm is “anytime” natively, in the sense that we cannot stop the computation at any time and receive an answer from the agent instantly. Strictly speaking, it is possible to develop an anytime version of some of the algorithms considered in BBRL. However, we made the choice to stay as close as possible to the original algorithms proposed in their respective papers for reasons of fairness. In consequence, although computation time is a.