Pancreatic necrosis and multiorgan failure. Diclophenac sodium together with indometacine is currently common remedy in prevention of PEP although ceftazidime is achievable option treatment for sufferers with contraindication for nonsteroidal antiinflammatory drugs (NSAID). Aims Strategies: The main aim of this study was to decide whether or not prophylactic,parenteraly administered ceftazidime reduces the frequency of PEP in comparison to rectally applied diclofenac sodium. All eligible patients who underwent ERCP in tertiary care center throughout a month period (June to February had been enrolled within this study. Estimating the prevalence of PEP of and reduction of incidence of ( beta) calculated total sample size was . In a doubleblinded randomized controlled trial,patients a suppository containing a mg of diclofenac sodium rectally and placebo intravenously (group A) or g of ceftazidime intravenously and placebo rectally (group B) quickly prior to the procedure. PEP was diagnosed based on the standardized criteria (Cotton criteria). The study was registered at Clinical Trial.gov (NCT) Final results: We included sufferers,imply age of . years (SD),female There had been patients within the diclofenac sodium group and within the ceftazidime group. The occurrence of postERCPPatients FCSEMS removability Total FCSEMS distal migration FCSEMS proximal migration MPD stricture resolution SEMS “induced” MPD stricture Asymptomatic A single patient excluded from followup (pancreatic cancer diagnosed months immediately after stent removal). Conclusion: FCSEMS removability from the MPD in chronic pancreatitis was feasible in all instances. After year followup of the sufferers have been asymptomatic; this figure is similar to these obtained with plastic stents. Occurrence of FCSEMS induced pancreatic strictures is usually a key issue and deserves further assessment. In line with our expertise the use of FCSEMS in the MPD demands cautious evaluation inside the setting of clinical trials.A Abstract quantity: P Biliary situation .Papillary stenosis,migrated CBD stones .Stones mm .Malignant extrahepatic strictures .Benign extrahepatic strictures .Biliary leaks .Stones mm .Hilar strictures . Lemmers Ulb Erasme,Brussels,Belgium,BSCI,Marborough,Usa Speak to Email Address: jacques.deviereerasme.ulb.ac.be Introduction: Several plastic stents are employed for calibrating distal stricture in extreme chronic pancreatitis. A single metal stent which will not require exchanges could be useful within this setting. Aims Methods: Document feasibility and preliminary security in ongoing pancreatic endotherapy in sufferers (pts) with painful chronic pancreatitis (CP) of Cremer Type IV utilizing a new Nitinol “Soft” completely covered ( mm diameter) selfexpanding metal stent (Panc SEMS) (Pancreatic WallFlex,Boston Scientific Corporation,Marlborough,USA). Ten individuals enrolled. Intended Panc SEMS indwell mo in pts and mo in pts. Followup to mo ongoing. Interim final results reported on ITT basis. Final results: pts (imply age , male). CP etiology alcoholic, hereditary, unknown. order ML240 Calcific CP in PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/21688206 of pts. All pts had prior plastic stent placement(s) in the course of a mean of yrs (range mo to yrs). No pts had a prior Panc SEMS. At time of interim analysis,all pts had been stent totally free with imply time on study d (variety d) and imply stentfree period of d (variety d). In total stents were placed,with pts possessing immediate removal and replacement of your initial stent resulting from deployment in unsatisfactory position and pts needing a second stent placement soon after prematu.