Product Name :
Cdc7-IN-1
Description:
Cdc7-IN-1 (Compound 13) is a highly potent, selective and ATP competitive inhibitor of Cdc7 kinase, with an IC50 value of 0.6 nM at 1 mM ATP and with slow off-rate characteristics. Cdc7-IN-1 potently inhibits Cdc7 activity in cancer cells, and effectively induces cell death.
CAS:
1402055-25-7
Molecular Weight:
409.82
Formula:
C21H16ClN3O4
Chemical Name:
ethyl 2-[(2-chlorophenyl)amino]-4-hydroxy-5-{[(3Z)-3H-pyrrolo[2,3-b]pyridin-3-ylidene]methyl}furan-3-carboxylate
Smiles :
CCOC(=O)C1C(O)=C(/C=C2\C=NC3=NC=CC=C\23)OC=1NC1=CC=CC=C1Cl
InChiKey:
MNEODYFHQBZJNQ-ZRDIBKRKSA-N
InChi :
InChI=1S/C21H16ClN3O4/c1-2-28-21(27)17-18(26)16(10-12-11-24-19-13(12)6-5-9-23-19)29-20(17)25-15-8-4-3-7-14(15)22/h3-11,25-26H,2H2,1H3/b12-10+
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Interferon alfa} web|{Interferon alfa} Immunology/Inflammation|{Interferon alfa} Protocol|{Interferon alfa} Data Sheet|{Interferon alfa} manufacturer|{Interferon alfa} Cancer}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Cdc7-IN-1 (Compound 13) is a highly potent, selective and ATP competitive inhibitor of Cdc7 kinase, with an IC50 value of 0.6 nM at 1 mM ATP and with slow off-rate characteristics. Cdc7-IN-1 potently inhibits Cdc7 activity in cancer cells, and effectively induces cell death.|Product information|CAS Number: 1402055-25-7|Molecular Weight: 409.82|Formula: C21H16ClN3O4|Chemical Name: ethyl 2-[(2-chlorophenyl)amino]-4-hydroxy-5-{[(3Z)-3H-pyrrolo[2,3-b]pyridin-3-ylidene]methyl}furan-3-carboxylate|Smiles: CCOC(=O)C1C(O)=C(/C=C2\C=NC3=NC=CC=C\23)OC=1NC1=CC=CC=C1Cl|InChiKey: MNEODYFHQBZJNQ-ZRDIBKRKSA-N|InChi: InChI=1S/C21H16ClN3O4/c1-2-28-21(27)17-18(26)16(10-12-11-24-19-13(12)6-5-9-23-19)29-20(17)25-15-8-4-3-7-14(15)22/h3-11,25-26H,2H2,1H3/b12-10+|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 5.{{Zalcitabine} web|{Zalcitabine} Anti-infection|{Zalcitabine} NF-κB|{Zalcitabine} Biological Activity|{Zalcitabine} In Vitro|{Zalcitabine} custom synthesis} 2 mg/mL (12.PMID:34816786 69 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|