Product Name :
TG-89, inhibitor of JAK2, FLT3, RET and JAK3
Description:
TG-89 is an inhibitor of JAK2 with IC50 of 11.2 μM.
CAS:
936091-56-4
Molecular Weight:
510.65
Formula:
C26H34N6O3S
Chemical Name:
N-tert-Butyl-3-[[5-methyl-2-[3-(morpholin-4-ylmethyl)anilino]pyrimidin-4-yl]amino]benzenesulfonamide
Smiles :
CC1=CN=C(NC2=CC(CN3CCOCC3)=CC=C2)N=C1NC1=CC(=CC=C1)S(=O)(=O)NC(C)(C)C
InChiKey:
OOSKXASFJFSOBK-UHFFFAOYSA-N
InChi :
InChI=1S/C26H34N6O3S/c1-19-17-27-25(29-21-8-5-7-20(15-21)18-32-11-13-35-14-12-32)30-24(19)28-22-9-6-10-23(16-22)36(33,34)31-26(2,3)4/h5-10,15-17,31H,11-14,18H2,1-4H3,(H2,27,28,29,30)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
TG-89 is an inhibitor of JAK2 with IC50 of 11.2 μM.|Product information|CAS Number: 936091-56-4|Molecular Weight: 510.65|Formula: C26H34N6O3S|Chemical Name: N-tert-Butyl-3-[[5-methyl-2-[3-(morpholin-4-ylmethyl)anilino]pyrimidin-4-yl]amino]benzenesulfonamide|Smiles: CC1=CN=C(NC2=CC(CN3CCOCC3)=CC=C2)N=C1NC1=CC(=CC=C1)S(=O)(=O)NC(C)(C)C|InChiKey: OOSKXASFJFSOBK-UHFFFAOYSA-N|InChi: InChI=1S/C26H34N6O3S/c1-19-17-27-25(29-21-8-5-7-20(15-21)18-32-11-13-35-14-12-32)30-24(19)28-22-9-6-10-23(16-22)36(33,34)31-26(2,3)4/h5-10,15-17,31H,11-14,18H2,1-4H3,(H2,27,28,29,30)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: Solubility (25°C) DMSO: 10 mg/mL(19.{{Nimorazole} MedChemExpress|{Nimorazole} Antibiotic|{Nimorazole} Protocol|{Nimorazole} Purity|{Nimorazole} custom synthesis|{Nimorazole} Autophagy} 58 mM).{{Bortezomib} site|{Bortezomib} NF-κB|{Bortezomib} Protocol|{Bortezomib} In Vitro|{Bortezomib} manufacturer|{Bortezomib} Autophagy} Water: ˂1 mg/mL.PMID:23439434 |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|References:|Kirill Gorshkov, et al. Transl Oncol. 2019 Mar;12(3):441-452.Products are for research use only. Not for human use.|