Product Name :
Cirsimaritin
Description:
Cirsimaritin binds weakly to the benzodiazepine site on GABAA receptors, with antidepressant, anxiolytic and antinociceptive activities.
CAS:
6601-62-3
Molecular Weight:
314.29
Formula:
C17H14O6
Chemical Name:
5-hydroxy-2-(4-hydroxyphenyl)-6,7-dimethoxy-4H-chromen-4-one
Smiles :
COC1C=C2OC(=CC(=O)C2=C(O)C=1OC)C1C=CC(O)=CC=1
InChiKey:
ZIIAJIWLQUVGHB-UHFFFAOYSA-N
InChi :
InChI=1S/C17H14O6/c1-21-14-8-13-15(16(20)17(14)22-2)11(19)7-12(23-13)9-3-5-10(18)6-4-9/h3-8,18,20H,1-2H3
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Cirsimaritin binds weakly to the benzodiazepine site on GABAA receptors, with antidepressant, anxiolytic and antinociceptive activities.|Product information|CAS Number: 6601-62-3|Molecular Weight: 314.29|Formula: C17H14O6|Chemical Name: 5-hydroxy-2-(4-hydroxyphenyl)-6,7-dimethoxy-4H-chromen-4-one|Smiles: COC1C=C2OC(=CC(=O)C2=C(O)C=1OC)C1C=CC(O)=CC=1|InChiKey: ZIIAJIWLQUVGHB-UHFFFAOYSA-N|InChi: InChI=1S/C17H14O6/c1-21-14-8-13-15(16(20)17(14)22-2)11(19)7-12(23-13)9-3-5-10(18)6-4-9/h3-8,18,20H,1-2H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 22.73 mg/mL (72.{{Demeclocycline} MedChemExpress|{Demeclocycline} Antibiotic|{Demeclocycline} Protocol|{Demeclocycline} In stock|{Demeclocycline} manufacturer|{Demeclocycline} Epigenetic Reader Domain} 32 mM; Need ultrasonic).{{Ibudilast} medchemexpress|{Ibudilast} Phosphodiesterase (PDE)|{Ibudilast} Protocol|{Ibudilast} In Vitro|{Ibudilast} supplier|{Ibudilast} Cancer} |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:24507727 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vivo:|Cirsimaritin significantly reduces the anxiety in mice. Cirsimaritin does not decrease by co-administration of flumazenil (2.5 mg/kg) with salvigenin, rosmanol and cirsimaritin (10 mg/kg), indicating that the high-affinity benzodiazepine binding site is not involved in the anxiolytic activity induced by these compounds.|Products are for research use only. Not for human use.|