Product Name :
Aminooxy-PEG2-azide
Description:
Aminooxy-PEG2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Aminooxy-PEG2-azide is also a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
CAS:
1043426-13-6
Molecular Weight:
190.20
Formula:
C6H14N4O3
Chemical Name:
O-{2-[2-(2-azidoethoxy)ethoxy]ethyl}hydroxylamine
Smiles :
[N-]=[N+]=NCCOCCOCCON
InChiKey:
GCURLNTZWQFVMK-UHFFFAOYSA-N
InChi :
InChI=1S/C6H14N4O3/c7-10-9-1-2-11-3-4-12-5-6-13-8/h1-6,8H2
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Carmofur} MedChemExpress|{Carmofur} SARS-CoV|{Carmofur} Epigenetics|{Carmofur} Protocol|{Carmofur} References|{Carmofur} supplier}
Additional information:
Aminooxy-PEG2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.{{Spartalizumab} medchemexpress|{Spartalizumab} Immunology/Inflammation|{Spartalizumab} Biological Activity|{Spartalizumab} Description|{Spartalizumab} supplier|{Spartalizumab} Epigenetic Reader Domain} Aminooxy-PEG2-azide is also a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).PMID:32727246 |Product information|CAS Number: 1043426-13-6|Molecular Weight: 190.20|Formula: C6H14N4O3|Chemical Name: O-{2-[2-(2-azidoethoxy)ethoxy]ethyl}hydroxylamine|Smiles: [N-]=[N+]=NCCOCCOCCON|InChiKey: GCURLNTZWQFVMK-UHFFFAOYSA-N|InChi: InChI=1S/C6H14N4O3/c7-10-9-1-2-11-3-4-12-5-6-13-8/h1-6,8H2|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.|Products are for research use only. Not for human use.|