Hydroxy-Amino-bis(PEG2-propargyl)

Product Name :
Hydroxy-Amino-bis(PEG2-propargyl)

Description:
Hydroxy-Amino-bis(PEG2-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

CAS:
2100306-77-0

Molecular Weight:
313.39

Formula:
C16H27NO5

Chemical Name:
2-(4,7,13,16-tetraoxa-10-azanonadeca-1,18-diyn-10-yl)ethan-1-ol

Smiles :
C#CCOCCOCCN(CCO)CCOCCOCC#C

InChiKey:
CFAWPKGCJLYIOW-UHFFFAOYSA-N

InChi :
InChI=1S/C16H27NO5/c1-3-9-19-13-15-21-11-6-17(5-8-18)7-12-22-16-14-20-10-4-2/h1-2,18H,5-16H2

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life:
≥12 months if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.

Additional information:
Hydroxy-Amino-bis(PEG2-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.|Product information|CAS Number: 2100306-77-0|Molecular Weight: 313.39|Formula: C16H27NO5|Chemical Name: 2-(4,7,13,16-tetraoxa-10-azanonadeca-1,18-diyn-10-yl)ethan-1-ol|Smiles: C#CCOCCOCCN(CCO)CCOCCOCC#C|InChiKey: CFAWPKGCJLYIOW-UHFFFAOYSA-N|InChi: InChI=1S/C16H27NO5/c1-3-9-19-13-15-21-11-6-17(5-8-18)7-12-22-16-14-20-10-4-2/h1-2,18H,5-16H2|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Abietic acid} site|{Abietic acid} Anti-infection|{Abietic acid} Purity & Documentation|{Abietic acid} In Vitro|{Abietic acid} custom synthesis|{Abietic acid} Autophagy} |Shelf Life: ≥12 months if stored properly.{{Varenicline} web|{Varenicline} Neuronal Signaling|{Varenicline} Protocol|{Varenicline} Description|{Varenicline} custom synthesis|{Varenicline} Autophagy} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:31869128 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|

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