Product Name :
GBR 12935
Description:
GBR-12935 is a piperazine derivative which is a potent and selective dopamine reuptake inhibitor. It was originally developed in its 3H radiolabelled form for the purpose of mapping the distribution of dopaminergic neurons in the brain by selective labelling of dopamine transporter proteins. This has led to potential clinical uses in the diagnosis of Parkinson’s disease, although selective radioligands such as Ioflupane (¹²³I) are now available for this application. GBR-12935 is now widely used in animal research into Parkinson’s disease and the dopamine pathways in the brain.
CAS:
76778-22-8
Molecular Weight:
414.58
Formula:
C28H34N2O
Chemical Name:
1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine
Smiles :
C(CCN1CCN(CCOC(C2C=CC=CC=2)C2C=CC=CC=2)CC1)C1C=CC=CC=1
InChiKey:
RAQPOZGWANIDQT-UHFFFAOYSA-N
InChi :
InChI=1S/C28H34N2O/c1-4-11-25(12-5-1)13-10-18-29-19-21-30(22-20-29)23-24-31-28(26-14-6-2-7-15-26)27-16-8-3-9-17-27/h1-9,11-12,14-17,28H,10,13,18-24H2
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
GBR-12935 is a piperazine derivative which is a potent and selective dopamine reuptake inhibitor. It was originally developed in its 3H radiolabelled form for the purpose of mapping the distribution of dopaminergic neurons in the brain by selective labelling of dopamine transporter proteins. This has led to potential clinical uses in the diagnosis of Parkinson’s disease, although selective radioligands such as Ioflupane (¹²³I) are now available for this application.Droxidopa Purity GBR-12935 is now widely used in animal research into Parkinson’s disease and the dopamine pathways in the brain.|Product information|CAS Number: 76778-22-8|Molecular Weight: 414.58|Formula: C28H34N2O|Synonym:|GBR12935|GBR-12935|Chemical Name: 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine|Smiles: C(CCN1CCN(CCOC(C2C=CC=CC=2)C2C=CC=CC=2)CC1)C1C=CC=CC=1|InChiKey: RAQPOZGWANIDQT-UHFFFAOYSA-N|InChi: InChI=1S/C28H34N2O/c1-4-11-25(12-5-1)13-10-18-29-19-21-30(22-20-29)23-24-31-28(26-14-6-2-7-15-26)27-16-8-3-9-17-27/h1-9,11-12,14-17,28H,10,13,18-24H2|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Telmisartan Biological Activity |Shelf Life: ≥12 months if stored properly.PMID:32639854 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|