Product Name :
Triclabendazole
Description:
Triclabendazole is an anthelmintic and fasciolicidal, binding to beta-tubulin and preventing the polymerization of the microtubules of which they are part. Studies in vitro and/or in infected animals suggest that triclabendazole and its active metabolites (sulfoxide and sulfone) are absorbed by the tegument of the immature and mature worms, leading to a decrease of the resting membrane potential, inhibition of tubulin function as well as protein and enzyme synthesis. These metabolic disturbances are associated with inhibition of motility, disruption of the surface as well as ultrastructure that includes inhibition of spermatogenesis and vitelline cells.
CAS:
68786-66-3
Molecular Weight:
359.Molnupiravir Epigenetic Reader Domain 66
Formula:
C14H9Cl3N2OS
Chemical Name:
5-chloro-6-(2,3-dichlorophenoxy)-2-(methylsulfanyl)-1H-1,3-benzodiazole
Smiles :
CSC1NC2=CC(OC3=CC=CC(Cl)=C3Cl)=C(Cl)C=C2N=1
InChiKey:
NQPDXQQQCQDHHW-UHFFFAOYSA-N
InChi :
InChI=1S/C14H9Cl3N2OS/c1-21-14-18-9-5-8(16)12(6-10(9)19-14)20-11-4-2-3-7(15)13(11)17/h2-6H,1H3,(H,18,19)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Dimethyl sulfoxide Bacterial
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:33316085
Additional information:
Triclabendazole is an anthelmintic and fasciolicidal, binding to beta-tubulin and preventing the polymerization of the microtubules of which they are part. Studies in vitro and/or in infected animals suggest that triclabendazole and its active metabolites (sulfoxide and sulfone) are absorbed by the tegument of the immature and mature worms, leading to a decrease of the resting membrane potential, inhibition of tubulin function as well as protein and enzyme synthesis. These metabolic disturbances are associated with inhibition of motility, disruption of the surface as well as ultrastructure that includes inhibition of spermatogenesis and vitelline cells.|Product information|CAS Number: 68786-66-3|Molecular Weight: 359.66|Formula: C14H9Cl3N2OS|Synonym:|Fasinex|CGA89317|Egaten|Endex-K|Chemical Name: 5-chloro-6-(2,3-dichlorophenoxy)-2-(methylsulfanyl)-1H-1,3-benzodiazole|Smiles: CSC1NC2=CC(OC3=CC=CC(Cl)=C3Cl)=C(Cl)C=C2N=1|InChiKey: NQPDXQQQCQDHHW-UHFFFAOYSA-N|InChi: InChI=1S/C14H9Cl3N2OS/c1-21-14-18-9-5-8(16)12(6-10(9)19-14)20-11-4-2-3-7(15)13(11)17/h2-6H,1H3,(H,18,19)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|