Product Name :
Bometolol Hydrochloride
Description:
Bometolol Hydrochloride is a beta-adrenergic blocking agent, used for the research of cardiovascular disease.
CAS:
65023-16-7
Molecular Weight:
508.99
Formula:
C25H33ClN2O7
Chemical Name:
5-(3-[2-(3,4-dimethoxyphenyl)ethyl]amino-2-hydroxypropoxy)-8-(2-oxopropoxy)-1,2,3,4-tetrahydroquinolin-2-one; chlorohydrogen
Smiles :
Cl.CC(=O)COC1=CC=C(OCC(O)CNCCC2C=C(OC)C(=CC=2)OC)C2CCC(=O)NC=21
InChiKey:
KCHIAYQOQVIORJ-UHFFFAOYSA-N
InChi :
InChI=1S/C25H32N2O7.ClH/c1-16(28)14-33-22-8-7-20(19-5-9-24(30)27-25(19)22)34-15-18(29)13-26-11-10-17-4-6-21(31-2)23(12-17)32-3;/h4,6-8,12,18,26,29H,5,9-11,13-15H2,1-3H3,(H,27,30);1H
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Siltuximab In Vivo
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Bometolol Hydrochloride is a beta-adrenergic blocking agent, used for the research of cardiovascular disease.Gemtuzumab Antibody-drug Conjugate/ADC Related |Product information|CAS Number: 65023-16-7|Molecular Weight: 508.99|Formula: C25H33ClN2O7|Chemical Name: 5-(3-[2-(3,4-dimethoxyphenyl)ethyl]amino-2-hydroxypropoxy)-8-(2-oxopropoxy)-1,2,3,4-tetrahydroquinolin-2-one; chlorohydrogen|Smiles: Cl.CC(=O)COC1=CC=C(OCC(O)CNCCC2C=C(OC)C(=CC=2)OC)C2CCC(=O)NC=21|InChiKey: KCHIAYQOQVIORJ-UHFFFAOYSA-N|InChi: InChI=1S/C25H32N2O7.ClH/c1-16(28)14-33-22-8-7-20(19-5-9-24(30)27-25(19)22)34-15-18(29)13-26-11-10-17-4-6-21(31-2)23(12-17)32-3;/h4,6-8,12,18,26,29H,5,9-11,13-15H2,1-3H3,(H,27,30);1H|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.PMID:32947642 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vivo:|Bometolol (10-30 mg/kg, p.o.) lowers the blood pressure dose-dependently in spontaneously hypertensive rats, deoxycorticosterone and salt hypertensive rats and two kindey, one clip hypertensive rats. In subchronic study, Bometolol (10-30 mg/kg, or 100-300 mg/kg, p.o.) dose-dependently decreases heart rate, plasma renin activity, heart and kindey weitht and incidence of vascular lesion, but shows no antihypertensive effects in all the hypertensive rats.|References:|Watanabe TX, et al. Acute and subchronic effects of bometolol on blood pressure in hypertensive rats. J Pharmacobiodyn. 1981 Jul;4(7):505-12.Products are for research use only. Not for human use.|