Product Name :
N-DBCO-N-bis(PEG2-C2-NHS ester)
Description:
N-DBCO-N-bis(PEG2-C2-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
CAS:
2128735-29-3
Molecular Weight:
818.82
Formula:
C41H46N4O14
Chemical Name:
2,5-dioxopyrrolidin-1-yl 3-{2-[2-(4-{2-azatricyclo[10.4.0.0⁴,⁹]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl}-N-[2-(2-{3-[(2,5-dioxopyrrolidin-1-yl)oxy]-3-oxopropoxy}ethoxy)ethyl]-4-oxobutanamido)ethoxy]ethoxy}propanoate
Smiles :
O=C(CCC(=O)N1CC2=CC=CC=C2C#CC2=CC=CC=C12)N(CCOCCOCCC(=O)ON1C(=O)CCC1=O)CCOCCOCCC(=O)ON1C(=O)CCC1=O
InChiKey:
KUJNKGPVOIXRHI-UHFFFAOYSA-N
InChi :
InChI=1S/C41H46N4O14/c46-34(11-12-35(47)43-29-32-7-2-1-5-30(32)9-10-31-6-3-4-8-33(31)43)42(19-23-56-27-25-54-21-17-40(52)58-44-36(48)13-14-37(44)49)20-24-57-28-26-55-22-18-41(53)59-45-38(50)15-16-39(45)51/h1-8H,11-29H2
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.{{Edaravone} MedChemExpress|{Edaravone} Metabolic Enzyme/Protease|{Edaravone} Protocol|{Edaravone} Purity|{Edaravone} supplier|{Edaravone} Autophagy}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Propranolol} site|{Propranolol} GPCR/G Protein|{Propranolol} Protocol|{Propranolol} In Vivo|{Propranolol} manufacturer|{Propranolol} Cancer}
Additional information:
N-DBCO-N-bis(PEG2-C2-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.PMID:24670464 |Product information|CAS Number: 2128735-29-3|Molecular Weight: 818.82|Formula: C41H46N4O14|Chemical Name: 2,5-dioxopyrrolidin-1-yl 3-{2-[2-(4-{2-azatricyclo[10.4.0.0⁴,⁹]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl}-N-[2-(2-{3-[(2,5-dioxopyrrolidin-1-yl)oxy]-3-oxopropoxy}ethoxy)ethyl]-4-oxobutanamido)ethoxy]ethoxy}propanoate|Smiles: O=C(CCC(=O)N1CC2=CC=CC=C2C#CC2=CC=CC=C12)N(CCOCCOCCC(=O)ON1C(=O)CCC1=O)CCOCCOCCC(=O)ON1C(=O)CCC1=O|InChiKey: KUJNKGPVOIXRHI-UHFFFAOYSA-N|InChi: InChI=1S/C41H46N4O14/c46-34(11-12-35(47)43-29-32-7-2-1-5-30(32)9-10-31-6-3-4-8-33(31)43)42(19-23-56-27-25-54-21-17-40(52)58-44-36(48)13-14-37(44)49)20-24-57-28-26-55-22-18-41(53)59-45-38(50)15-16-39(45)51/h1-8H,11-29H2|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|