Product Name :
DBCO-NHCO-PEG5-NHS ester
Description:
DBCO-NHCO-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
CAS:
1378531-80-6
Molecular Weight:
693.74
Formula:
C36H43N3O11
Chemical Name:
2,5-dioxopyrrolidin-1-yl 1-[(3-{2-azatricyclo[10.4.0.0⁴,⁹]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl}-3-oxopropyl)carbamoyl]-3,6,9,12,15-pentaoxaoctadecan-18-oate
Smiles :
O=C(CCNC(=O)CCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O)N1CC2=CC=CC=C2C#CC2=CC=CC=C12
InChiKey:
VGKLBFTYZNBCQG-UHFFFAOYSA-N
InChi :
InChI=1S/C36H43N3O11/c40-32(37-16-13-33(41)38-27-30-7-2-1-5-28(30)9-10-29-6-3-4-8-31(29)38)14-17-45-19-21-47-23-25-49-26-24-48-22-20-46-18-15-36(44)50-39-34(42)11-12-35(39)43/h1-8H,11-27H2,(H,37,40)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
DBCO-NHCO-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.|Product information|CAS Number: 1378531-80-6|Molecular Weight: 693.74|Formula: C36H43N3O11|Chemical Name: 2,5-dioxopyrrolidin-1-yl 1-[(3-{2-azatricyclo[10.4.0.0⁴,⁹]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl}-3-oxopropyl)carbamoyl]-3,6,9,12,15-pentaoxaoctadecan-18-oate|Smiles: O=C(CCNC(=O)CCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O)N1CC2=CC=CC=C2C#CC2=CC=CC=C12|InChiKey: VGKLBFTYZNBCQG-UHFFFAOYSA-N|InChi: InChI=1S/C36H43N3O11/c40-32(37-16-13-33(41)38-27-30-7-2-1-5-28(30)9-10-29-6-3-4-8-31(29)38)14-17-45-19-21-47-23-25-49-26-24-48-22-20-46-18-15-36(44)50-39-34(42)11-12-35(39)43/h1-8H,11-27H2,(H,37,40)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{CPS2} site|{CPS2} Cell Cycle/DNA Damage|{CPS2} Technical Information|{CPS2} Formula|{CPS2} supplier|{CPS2} Autophagy} |Shelf Life: ≥12 months if stored properly.{{NAT} MedChemExpress|{NAT} NAMPT|{NAT} Purity & Documentation|{NAT} In Vitro|{NAT} manufacturer|{NAT} Autophagy} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:23543429 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|