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Ms-PEG8-Boc

Product Name :
Ms-PEG8-Boc

Description:
Ms-PEG8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

CAS:
2097604-01-6

Molecular Weight:
576.70

Formula:
C24H48O13S

Chemical Name:
tert-butyl 1-(methanesulfonyloxy)-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oate

Smiles :
CC(C)(C)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOS(C)(=O)=O

InChiKey:
ARFPSYCSFDJABG-UHFFFAOYSA-N

InChi :
InChI=1S/C24H48O13S/c1-24(2,3)37-23(25)5-6-28-7-8-29-9-10-30-11-12-31-13-14-32-15-16-33-17-18-34-19-20-35-21-22-36-38(4,26)27/h5-22H2,1-4H3

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Semaglutide} MedChemExpress|{Semaglutide} GPCR/G Protein|{Semaglutide} Purity & Documentation|{Semaglutide} In stock|{Semaglutide} custom synthesis|{Semaglutide} Cancer}

Shelf Life:
≥12 months if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.

Additional information:
Ms-PEG8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.{{Abatacept} site|{Abatacept} CTLA-4|{Abatacept} Purity & Documentation|{Abatacept} In stock|{Abatacept} supplier|{Abatacept} Epigenetics} |Product information|CAS Number: 2097604-01-6|Molecular Weight: 576.PMID:32589561 70|Formula: C24H48O13S|Chemical Name: tert-butyl 1-(methanesulfonyloxy)-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oate|Smiles: CC(C)(C)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOS(C)(=O)=O|InChiKey: ARFPSYCSFDJABG-UHFFFAOYSA-N|InChi: InChI=1S/C24H48O13S/c1-24(2,3)37-23(25)5-6-28-7-8-29-9-10-30-11-12-31-13-14-32-15-16-33-17-18-34-19-20-35-21-22-36-38(4,26)27/h5-22H2,1-4H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|

MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com

Rat IgG2a Isotype Control

Product Name :
Rat IgG2a Isotype Control

Applications:
Isotype Control

Reactivity :

Conjugate:
Unconjugated

Advantages :
High lot-to-lot consistencyAnimal-free production

Description:
| Description: Rat IgG2a Isotype Control is designed as a negative control in Rat IgG2a antibody staining applications.{{2851058-71-2} site|{2851058-71-2} Protocol|{2851058-71-2} Formula|{2851058-71-2} supplier} Rat IgG2a Isotype Control belongs to the same immunoglobulin class and subclass as the Rat IgG2a antibody which is used in the experiment but lack affinity to the protein of interest. Rat IgG2a Isotype Control has no antigen-binding capacity, and it makes experiments credible, | Isotype: Rat IgG2a(kappa) | Conjugate: Unconjugated | Purity: Recombinant Expression and Affinity purified | Concentration: 1mg/ml | Formation: Liquid, 10mM PBS (pH 7.5) | Storage: Store at –20 °C, (Avoid freeze / thaw cycles) | Background:Antibodies bind to a specific protein or antigen, but sometimes an antibody can bind to other proteins or cellular components in a non-specific manner. Experimental controls are critical in determining if the antibodies used in your experiment have any off-target binding capabilities. Off-target or non-specific binding by antibodies lead to false positive results, making it difficult to determine background staining from antigen-specific staining. Therefore, it is important to always include experimental controls to ensure reliable results.

Description2 :
Rat IgG2a Isotype Control is designed as a negative control in Rat IgG2a antibody staining applications. Rat IgG2a Isotype Control belongs to the same immunoglobulin class and subclass as the Rat IgG2a antibody which is used in the experiment but lack affinity to the protein of interest.{{210344-98-2} site|{210344-98-2} Technical Information|{210344-98-2} References|{210344-98-2} custom synthesis} Rat IgG2a Isotype Control has no antigen-binding capacity, and it makes experiments credible,

Immunogen:

Host :

Isotype:
Rat IgG2a(kappa)

Purity :
Recombinant Expression and Affinity purified

Buffer :

Storage :
Store at –20 °C, (Avoid freeze / thaw cycles)

Function:
Using at a dilution as the test antibody which is used in the experiment.PMID:30571046

Anti-Mouse IgG&Rabbit IgG for WB, AlpSdAbs® VHH(HRP)

Product Name :
Anti-Mouse IgG&Rabbit IgG for WB, AlpSdAbs® VHH(HRP)

Applications:
WB

Reactivity :
Mouse IgG&Rabbit IgG

Conjugate:
HRP

Advantages :
High lot-to-lot consistencyIncreased sensitivity and higher affinityAnimal-free production

Description:
| Description: Anti-Mouse IgG&Rabbit IgG for WB, AlpSdAbs® VHH(HRP) is designed for detecting both mouse IgG and rabbit IgG in western blot experiment specifically. Anti-Mouse IgG&Rabbit IgG for WB, AlpSdAbs® VHH(HRP) is based on recombinant single domain antibodies to mouse IgG(H+L) and rabbit IgG(H+L) coupled to HRP. Based on immunoelectrophoresis and/or ELISA, Anti-Mouse IgG&Rabbit IgG for WB, AlpSdAbs® VHH(HRP) detects the mouse IgG and rabbit IgG, no reactivity with human, cynomolgus, rat, goat IgG. | Immunogen: Recombinant mouse IgG/rabbit IgG | Host: Alpaca pacous | Isotype: VHH domain of alpaca IgG2b/2c | Conjugate: HRP | Specificity: Mouse IgG&Rabbit IgG | Cross-Reactivity: No cross-reactivity with human, cynomolgus, rat, goat IgG | Purity: Recombinant Expression and Affinity purified | Concentration: 1mg/mL | Formation: Liquid, 10mM PBS (pH 7.{{2022215-65-0} web|{2022215-65-0} Purity & Documentation|{2022215-65-0} Description|{2022215-65-0} supplier} 5), 0.05% sucrose, 0.1% trehalose, 0.01% proclin300, 50% glycerol | Storage: Store at –20 °C(Avoid freeze / thaw cycles), Protect from light. | Background:VHH are single-domain antibodies derived from the variable regions of heavy chain of Camelidae immunoglobulin. The size of VHH is extremely small(

Description2 :
Anti-Mouse IgG&Rabbit IgG for WB, AlpSdAbs® VHH(HRP) is designed for detecting both mouse IgG and rabbit IgG in western blot experiment specifically. Anti-Mouse IgG&Rabbit IgG for WB, AlpSdAbs® VHH(HRP) is based on recombinant single domain antibodies to mouse IgG(H+L) and rabbit IgG(H+L) coupled to HRP. Based on immunoelectrophoresis and/or ELISA, Anti-Mouse IgG&Rabbit IgG for WB, AlpSdAbs® VHH(HRP) detects the mouse IgG and rabbit IgG, no reactivity with human, cynomolgus, rat, goat IgG.{{146986-50-7} MedChemExpress|{146986-50-7} Biological Activity|{146986-50-7} Data Sheet|{146986-50-7} manufacturer}

Immunogen:
Recombinant mouse IgG/rabbit IgG

Host :
Alpaca pacous

Isotype:
VHH domain of alpaca IgG2b/2c

Purity :
Recombinant Expression and Affinity purified

Buffer :

Storage :
Store at –20 °C(Avoid freeze / thaw cycles), Protect from light.PMID:30521230

Function:
WB: 1:10000-1:50000WB: 1:2000(For preincubation with First antibody)Dilution factors are presented in the form of a range because the optimal dilution is a function of many factors, such as antigen density, permeability, etc. The actual dilution used must be determined empirically.

1-Eicosanol

Product Name :
1-Eicosanol

Description:
1-Eicosanol is a natural compound with antioxidant activity isolated from Hypericum carinatum.

CAS:
629-96-9

Molecular Weight:
298.55

Formula:
C20H42O

Chemical Name:
icosan-1-ol

Smiles :
CCCCCCCCCCCCCCCCCCCCO

InChiKey:
BTFJIXJJCSYFAL-UHFFFAOYSA-N

InChi :
InChI=1S/C20H42O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21/h21H,2-20H2,1H3

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life:
≥12 months if stored properly.{{Docetaxel} medchemexpress|{Docetaxel} Apoptosis|{Docetaxel} Biological Activity|{Docetaxel} In Vitro|{Docetaxel} supplier|{Docetaxel} Autophagy}

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.

Additional information:
1-Eicosanol is a natural compound with antioxidant activity isolated from Hypericum carinatum.|Product information|CAS Number: 629-96-9|Molecular Weight: 298.{{α-MSH} site|{α-MSH} Melanocortin Receptor|{α-MSH} NF-κB|{α-MSH} Biological Activity|{α-MSH} In stock|{α-MSH} supplier} 55|Formula: C20H42O|Chemical Name: icosan-1-ol|Smiles: CCCCCCCCCCCCCCCCCCCCO|InChiKey: BTFJIXJJCSYFAL-UHFFFAOYSA-N|InChi: InChI=1S/C20H42O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21/h21H,2-20H2,1H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:32061246 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|

Anti-PDL1/CD274(Pacmilimab Biosimilar) Antibody

Product Name :
Anti-PDL1/CD274(Pacmilimab Biosimilar) Antibody

Applications:
ELISA,Flow Cyt

Reactivity :
Human PDL1/CD274

Conjugate:
Unconjugated

Advantages :
High lot-to-lot consistencyIncreased sensitivity and higher affinityAnimal-free production

Description:
| Description: Anti-PDL1/CD274(Pacmilimab Biosimilar) Antibody is a biosimilar antibody directed against Human PDL1/CD274. | Isotype: Human IgG4 | Conjugate: Unconjugated | Specificity: Human PDL1/CD274 | Clonality: Monoclonal | Purity: Recombinant Expression and Affinity purified | Concentration: 1mg/ml | Formation: Liquid, 10mM PBS (pH 7.{{3258-02-4} medchemexpress|{3258-02-4} Biological Activity|{3258-02-4} References|{3258-02-4} custom synthesis} 5) | Storage: Store at –20 °C, (Avoid freeze/thaw cycles)

Description2 :
Anti-PDL1/CD274(Pacmilimab Biosimilar) Antibody is a biosimilar antibody directed against Human PDL1/CD274.{{1421373-65-0} web|{1421373-65-0} Technical Information|{1421373-65-0} In Vivo|{1421373-65-0} manufacturer}

Immunogen:

Host :

Isotype:
Human IgG4

Purity :
Recombinant Expression and Affinity purified

Buffer :

Storage :

Function:
ELISA: 1:5000-1:20000Flow Cyt: 1:200-1:1000Other tested applications.PMID:30860759 Dilution factors are presented in the form of a range because the optimal dilution is a function of many factors, such as antigen density, permeability, etc. The actual dilution used must be determined empirically.

Anti-NOTCH2 and NOTCH3(Tarextumab Biosimilar) Antibody

Product Name :
Anti-NOTCH2 and NOTCH3(Tarextumab Biosimilar) Antibody

Applications:
ELISA,Flow Cyt

Reactivity :
Human NOTCH2 and NOTCH3

Conjugate:
Unconjugated

Advantages :
High lot-to-lot consistencyIncreased sensitivity and higher affinityAnimal-free production

Description:
| Description: Anti-NOTCH2 and NOTCH3(Tarextumab Biosimilar) Antibody is a biosimilar antibody directed against Human NOTCH2 and NOTCH3. | Isotype: Human IgG2 | Conjugate: Unconjugated | Specificity: Human NOTCH2 and NOTCH3 | Clonality: Monoclonal | Purity: Recombinant Expression and Affinity purified | Concentration: 1mg/ml | Formation: Liquid, 10mM PBS (pH 7.{{17397-89-6} web|{17397-89-6} Protocol|{17397-89-6} In Vitro|{17397-89-6} custom synthesis} 5) | Storage: Store at –20 °C, (Avoid freeze/thaw cycles)

Description2 :
Anti-NOTCH2 and NOTCH3(Tarextumab Biosimilar) Antibody is a biosimilar antibody directed against Human NOTCH2 and NOTCH3.{{1309601-26-0} site|{1309601-26-0} Protocol|{1309601-26-0} In Vivo|{1309601-26-0} supplier}

Immunogen:

Host :

Isotype:
Human IgG2

Purity :
Recombinant Expression and Affinity purified

Buffer :

Storage :

Function:
ELISA: 1:5000-1:20000Flow Cyt: 1:200-1:1000Other tested applications.PMID:30020662 Dilution factors are presented in the form of a range because the optimal dilution is a function of many factors, such as antigen density, permeability, etc. The actual dilution used must be determined empirically.

Fmoc-8-amino-3, 6-dioxaoctanoic acid

Product Name :
Fmoc-8-amino-3, 6-dioxaoctanoic acid

Description:
Fmoc-8-amino-3, 6-dioxaoctanoic acid (Fmoc-NH-PEG2-CH2COOH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-8-amino-3, 6-dioxaoctanoic acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

CAS:
166108-71-0

Molecular Weight:
385.41

Formula:
C21H23NO6

Chemical Name:
2-{2-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)ethoxy]ethoxy}acetic acid

Smiles :
OC(=O)COCCOCCNC(=O)OCC1C2=CC=CC=C2C2=CC=CC=C21

InChiKey:
XQPYRJIMPDBGRW-UHFFFAOYSA-N

InChi :
InChI=1S/C21H23NO6/c23-20(24)14-27-12-11-26-10-9-22-21(25)28-13-19-17-7-3-1-5-15(17)16-6-2-4-8-18(16)19/h1-8,19H,9-14H2,(H,22,25)(H,23,24)

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life:
≥360 days if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.

Additional information:
Fmoc-8-amino-3, 6-dioxaoctanoic acid (Fmoc-NH-PEG2-CH2COOH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).{{Mephenytoin} MedChemExpress|{Mephenytoin} Metabolic Enzyme/Protease|{Mephenytoin} TGF-beta/Smad|{Mephenytoin} Technical Information|{Mephenytoin} Description|{Mephenytoin} manufacturer} Fmoc-8-amino-3, 6-dioxaoctanoic acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.{{Nourseothricin} site|{Nourseothricin} Inhibitor|{Nourseothricin} NF-κB|{Nourseothricin} Technical Information|{Nourseothricin} In stock|{Nourseothricin} manufacturer} |Product information|CAS Number: 166108-71-0|Molecular Weight: 385.41|Formula: C21H23NO6|Synonym:|Fmoc-NH-PEG2-CH2COOH|Chemical Name: 2-{2-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)ethoxy]ethoxy}acetic acid|Smiles: OC(=O)COCCOCCNC(=O)OCC1C2=CC=CC=C2C2=CC=CC=C21|InChiKey: XQPYRJIMPDBGRW-UHFFFAOYSA-N|InChi: InChI=1S/C21H23NO6/c23-20(24)14-27-12-11-26-10-9-22-21(25)28-13-19-17-7-3-1-5-15(17)16-6-2-4-8-18(16)19/h1-8,19H,9-14H2,(H,22,25)(H,23,24)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: Soluble in DMSO.|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:32463711 |Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|References:|Nakamura A, et al. Chemogenetic Control of Protein Anchoring to Endomembranes in Living Cells with Lipid-Tethered Small Molecules. Biochemistry. 2020 Jan 21;59(2):205-211.Products are for research use only. Not for human use.|

Anti-ENTPD1/CD39(Eurestobart Biosimilar) Antibody

Product Name :
Anti-ENTPD1/CD39(Eurestobart Biosimilar) Antibody

Applications:
ELISA,Flow Cyt

Reactivity :
Human ENTPD1/CD39

Conjugate:
Unconjugated

Advantages :
High lot-to-lot consistencyIncreased sensitivity and higher affinityAnimal-free production

Description:
| Description: Anti-ENTPD1/CD39(Eurestobart Biosimilar) Antibody is a biosimilar antibody directed against Human ENTPD1/CD39. | Isotype: Human IgG1 | Conjugate: Unconjugated | Specificity: Human ENTPD1/CD39 | Clonality: Monoclonal | Purity: Recombinant Expression and Affinity purified | Concentration: 1mg/ml | Formation: Liquid, 10mM PBS (pH 7.{{3184-13-2} web|{3184-13-2} Protocol|{3184-13-2} References|{3184-13-2} manufacturer} 5) | Storage: Store at –20 °C, (Avoid freeze/thaw cycles)

Description2 :
Anti-ENTPD1/CD39(Eurestobart Biosimilar) Antibody is a biosimilar antibody directed against Human ENTPD1/CD39.

Immunogen:

Host :

Isotype:
Human IgG1

Purity :
Recombinant Expression and Affinity purified

Buffer :

Storage :

Function:
ELISA: 1:5000-1:20000Flow Cyt: 1:200-1:1000Other tested applications.{{446859-33-2} web|{446859-33-2} Technical Information|{446859-33-2} Purity|{446859-33-2} supplier} Dilution factors are presented in the form of a range because the optimal dilution is a function of many factors, such as antigen density, permeability, etc.PMID:30285389 The actual dilution used must be determined empirically.

Anti-EGFL7(Parsatuzumab Biosimilar) Antibody

Product Name :
Anti-EGFL7(Parsatuzumab Biosimilar) Antibody

Applications:
ELISA,Flow Cyt

Reactivity :
Human EGFL7

Conjugate:
Unconjugated

Advantages :
High lot-to-lot consistencyIncreased sensitivity and higher affinityAnimal-free production

Description2 :
Anti-EGFL7(Parsatuzumab Biosimilar) Antibody is a biosimilar antibody directed against Human EGFL7.{{2316817-88-4} MedChemExpress|{2316817-88-4} Technical Information|{2316817-88-4} Formula|{2316817-88-4} custom synthesis}

Immunogen:

Host :

Isotype:
Human IgG1

Purity :
Recombinant Expression and Affinity purified

Buffer :

Storage :

Function:
ELISA: 1:5000-1:20000Flow Cyt: 1:200-1:1000Other tested applications.{{1247879-16-8} MedChemExpress|{1247879-16-8} Technical Information|{1247879-16-8} In Vivo|{1247879-16-8} manufacturer} Dilution factors are presented in the form of a range because the optimal dilution is a function of many factors, such as antigen density, permeability, etc.PMID:25905317 The actual dilution used must be determined empirically.

Anti-Human SERPINE1/PAI-1, AlpSdAbs® VHH

Product Name :
Anti-Human SERPINE1/PAI-1, AlpSdAbs® VHH

Applications:
ELISA

Reactivity :
Human SERPINE1/PAI-1

Conjugate:
Unconjugated

Advantages :
High lot-to-lot consistencyAnimal-free production

Description:
| Description: Anti-Human SERPINE1/PAI-1, AlpSdAbs® VHH is designed for detecting Human SERPINE1/PAI-1, and Anti-Human SERPINE1/PAI-1, AlpSdAbs® VHH is monoclonal, recombinant, single domain antibody.{{1613695-14-9} site|{1613695-14-9} Purity & Documentation|{1613695-14-9} Description|{1613695-14-9} manufacturer} | Immunogen: Human SERPINE1/PAI-1 | Host: Alpaca pacous | Isotype: VHH(8*His-HA tag-Cys) | Conjugate: Unconjugated | Specificity: Human SERPINE1/PAI-1 | Purity: Recombinant Expression and Affinity purified | Concentration: 1mg/ml | Formation: Liquid, 10mM PBS (pH 7.{{2064175-41-1} medchemexpress|{2064175-41-1} Purity & Documentation|{2064175-41-1} Purity|{2064175-41-1} custom synthesis} 5) | Storage: Store at –20 °C(Avoid freeze / thaw cycles)

Description2 :
Anti-Human SERPINE1/PAI-1, AlpSdAbs® VHH is designed for detecting Human SERPINE1/PAI-1, and Anti-Human SERPINE1/PAI-1, AlpSdAbs® VHH is monoclonal, recombinant, single domain antibody.PMID:27336129

Immunogen:
Human SERPINE1/PAI-1

Host :
Alpaca pacous

Isotype:
VHH(8*His-HA tag-Cys)

Purity :
Recombinant Expression and Affinity purified

Buffer :

Storage :

Function: